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Page 1
PLK1 overexpression suppresses homologous recombination and confers cellular sensitivity to PARP inhibition.
Pae S, Sedukhina AS, Sugiyama R, Atanacio SJ, Ohara T, Ishii M, Minagawa K, Akichjev R, Go F, Chandankeri Z, Janjetic ZMM, Sato E, Yamaura A, Meguro R, Palanisamy K, Maeda I, Takeuchi O, Suzuki N, Yudo K, Bernal JA, Sato K. Pae S, et al. Among authors: sedukhina as. Sci Rep. 2024 Dec 28;14(1):31276. doi: 10.1038/s41598-024-82724-w. Sci Rep. 2024. PMID: 39732958 Free PMC article.
Quantitative imaging of RAD51 expression as a marker of platinum resistance in ovarian cancer.
Hoppe MM, Jaynes P, Wardyn JD, Upadhyayula SS, Tan TZ, Lie S, Lim DGZ, Pang BNK, Lim S, P S Yeong J, Karnezis A, Chiu DS, Leung S, Huntsman DG, Sedukhina AS, Sato K, Topp MD, Scott CL, Choi H, Patel NR, Brown R, Kaye SB, Pitt JJ, Tan DSP, Jeyasekharan AD. Hoppe MM, et al. Among authors: sedukhina as. EMBO Mol Med. 2021 May 7;13(5):e13366. doi: 10.15252/emmm.202013366. Epub 2021 Mar 11. EMBO Mol Med. 2021. PMID: 33709473 Free PMC article.
A new bioinformatics approach identifies overexpression of GRB2 as a poor prognostic biomarker for prostate cancer.
Iwata T, Sedukhina AS, Kubota M, Oonuma S, Maeda I, Yoshiike M, Usuba W, Minagawa K, Hames E, Meguro R, Cho S, Chien SHH, Urabe S, Pae S, Palanisamy K, Kumai T, Yudo K, Kikuchi E, Sato K. Iwata T, et al. Among authors: sedukhina as. Sci Rep. 2021 Mar 11;11(1):5696. doi: 10.1038/s41598-021-85086-9. Sci Rep. 2021. PMID: 33707553 Free PMC article.
NF-kB signaling in cardiomyocytes is inhibited by sevoflurane and promoted by propofol.
Oda-Kawashima K, Sedukhina AS, Okamoto N, Lytvyn M, Minagawa K, Iwata T, Kumai T, Sato E, Inada E, Yamaura A, Sakamoto M, Roche-Molina M, Bernal JA, Sato K. Oda-Kawashima K, et al. Among authors: sedukhina as. FEBS Open Bio. 2020 Feb;10(2):259-267. doi: 10.1002/2211-5463.12783. Epub 2020 Jan 15. FEBS Open Bio. 2020. PMID: 31898867 Free PMC article.
A bioinformatics-to-clinic sequential approach to analysis of prostate cancer biomarkers using TCGA datasets and clinical samples: a new method for precision oncology?
Yoshie H, Sedukhina AS, Minagawa K, Oda K, Ohnuma S, Yanagisawa N, Maeda I, Takagi M, Kudo H, Nakazawa R, Sasaki H, Kumai T, Chikaraishi T, Sato K. Yoshie H, et al. Among authors: sedukhina as. Oncotarget. 2017 Aug 24;8(59):99601-99611. doi: 10.18632/oncotarget.20448. eCollection 2017 Nov 21. Oncotarget. 2017. PMID: 29245927 Free PMC article.
NF-κB signaling mediates acquired resistance after PARP inhibition.
Nakagawa Y, Sedukhina AS, Okamoto N, Nagasawa S, Suzuki N, Ohta T, Hattori H, Roche-Molina M, Narváez AJ, Jeyasekharan AD, Bernal JA, Sato K. Nakagawa Y, et al. Among authors: sedukhina as. Oncotarget. 2015 Feb 28;6(6):3825-39. doi: 10.18632/oncotarget.2868. Oncotarget. 2015. PMID: 25686825 Free PMC article.
LSD1 overexpression is associated with poor prognosis in basal-like breast cancer, and sensitivity to PARP inhibition.
Nagasawa S, Sedukhina AS, Nakagawa Y, Maeda I, Kubota M, Ohnuma S, Tsugawa K, Ohta T, Roche-Molina M, Bernal JA, Narváez AJ, Jeyasekharan AD, Sato K. Nagasawa S, et al. Among authors: sedukhina as. PLoS One. 2015 Feb 13;10(2):e0118002. doi: 10.1371/journal.pone.0118002. eCollection 2015. PLoS One. 2015. PMID: 25679396 Free PMC article.