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HDAC6 inhibition disrupts HDAC6-P300 interaction reshaping the cancer chromatin landscape.
Zamperla MG, Illi B, Barbi V, Cencioni C, Santoni D, Gagliardi S, Garofalo M, Zingale GA, Pandino I, Sbardella D, Cipolla L, Sabbioneda S, Farsetti A, Ripamonti C, Fossati G, Steinkühler C, Gaetano C, Atlante S. Zamperla MG, et al. Among authors: steinkuhler c. Clin Epigenetics. 2024 Aug 18;16(1):109. doi: 10.1186/s13148-024-01725-8. Clin Epigenetics. 2024. PMID: 39155390 Free PMC article.
In vitro and in vivo evaluation of Bombesin-MMAE conjugates for targeted tumour therapy.
Gomena J, Modena D, Cordella P, Vári B, Ranđelović I, Borbély A, Bottani M, Vári-Mező D, Halmos G, Juhász É, Steinkühler C, Tóvári J, Mező G. Gomena J, et al. Among authors: steinkuhler c. Eur J Med Chem. 2024 Nov 5;277:116767. doi: 10.1016/j.ejmech.2024.116767. Epub 2024 Aug 13. Eur J Med Chem. 2024. PMID: 39146832 Free article.
Mechanistic and Structural Insights on Difluoromethyl-1,3,4-oxadiazole Inhibitors of HDAC6.
Cellupica E, Gaiassi A, Rocchio I, Rovelli G, Pomarico R, Sandrone G, Caprini G, Cordella P, Cukier C, Fossati G, Marchini M, Bebel A, Airoldi C, Palmioli A, Stevenazzi A, Steinkühler C, Vergani B. Cellupica E, et al. Among authors: steinkuhler c. Int J Mol Sci. 2024 May 28;25(11):5885. doi: 10.3390/ijms25115885. Int J Mol Sci. 2024. PMID: 38892072 Free PMC article.
Translation of paclitaxel-induced peripheral neurotoxicity from mice to patients: the importance of model selection.
Cavaletti G, Alberti P, Canta A, Carozzi V, Cherchi L, Chiorazzi A, Crippa L, Marmiroli P, Meregalli C, Pozzi E, Rodriguez-Menendez V, Steinkühler C, Licandro SA. Cavaletti G, et al. Among authors: steinkuhler c. Pain. 2024 Nov 1;165(11):2482-2493. doi: 10.1097/j.pain.0000000000003268. Epub 2024 May 2. Pain. 2024. PMID: 38723182 Free PMC article.
The Novel SSTR3 Agonist ITF2984 Exerts Antimitotic and Proapoptotic Effects in Human Non-Functioning Pituitary Neuroendocrine Tumor (NF-PitNET) Cells.
Di Muro G, Catalano R, Treppiedi D, Barbieri AM, Mangili F, Marra G, Di Bari S, Esposito E, Nozza E, Lania AG, Ferrante E, Locatelli M, Modena D, Steinkuhler C, Peverelli E, Mantovani G. Di Muro G, et al. Among authors: steinkuhler c. Int J Mol Sci. 2024 Mar 23;25(7):3606. doi: 10.3390/ijms25073606. Int J Mol Sci. 2024. PMID: 38612419 Free PMC article.
Inhibition of the lysine demethylase LSD1 modulates the balance between inflammatory and antiviral responses against coronaviruses.
Mazzarella L, Santoro F, Ravasio R, Fumagalli V, Massa PE, Rodighiero S, Gavilán E, Romanenghi M, Duso BA, Bonetti E, Manganaro L, Pallavi R, Trastulli D, Pallavicini I, Gentile C, Monzani S, Leonardi T, Pasqualato S, Buttinelli G, Di Martino A, Fedele G, Schiavoni I, Stefanelli P, Meroni G, de Francesco R, Steinkuhler C, Fossati G, Iannacone M, Minucci S, Pelicci PG. Mazzarella L, et al. Among authors: steinkuhler c. Sci Signal. 2023 Dec 19;16(816):eade0326. doi: 10.1126/scisignal.ade0326. Epub 2023 Dec 19. Sci Signal. 2023. PMID: 38113337
123 results