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Page 1
Increasing hub disruption parallels dementia severity in autosomal dominant Alzheimer's disease.
Tu JC, Millar PR, Strain JF, Eck A, Adeyemo B, Snyder AZ, Daniels A, Karch C, Huey ED, McDade E, Day GS, Yakushev I, Hassenstab J, Morris J, Llibre-Guerra JJ, Ibanez L, Jucker M, Mendez PC, Perrin RJ, Benzinger TLS, Jack CR Jr, Betzel R, Ances BM, Eggebrecht AT, Gordon BA, Wheelock MD; Dominantly Inherited Alzheimer Network. Tu JC, et al. Among authors: huey ed. Netw Neurosci. 2024 Dec 10;8(4):1265-1290. doi: 10.1162/netn_a_00395. eCollection 2024. Netw Neurosci. 2024. PMID: 39735502 Free PMC article.
Downstream Biomarker Effects of Gantenerumab or Solanezumab in Dominantly Inherited Alzheimer Disease: The DIAN-TU-001 Randomized Clinical Trial.
Wagemann O, Liu H, Wang G, Shi X, Bittner T, Scelsi MA, Farlow MR, Clifford DB, Supnet-Bell C, Santacruz AM, Aschenbrenner AJ, Hassenstab JJ, Benzinger TLS, Gordon BA, Coalier KA, Cruchaga C, Ibanez L, Perrin RJ, Xiong C, Li Y, Morris JC, Lah JJ, Berman SB, Roberson ED, van Dyck CH, Galasko D, Gauthier S, Hsiung GR, Brooks WS, Pariente J, Mummery CJ, Day GS, Ringman JM, Mendez PC, St George-Hyslop P, Fox NC, Suzuki K, Okhravi HR, Chhatwal J, Levin J, Jucker M, Sims JR, Holdridge KC, Proctor NK, Yaari R, Andersen SW, Mancini M, Llibre-Guerra J, Bateman RJ, McDade E; Dominantly Inherited Alzheimer Network–Trials Unit. Wagemann O, et al. JAMA Neurol. 2024 Jun 1;81(6):582-593. doi: 10.1001/jamaneurol.2024.0991. JAMA Neurol. 2024. PMID: 38683602 Free PMC article. Clinical Trial.
γ-Secretase activity, clinical features, and biomarkers of autosomal dominant Alzheimer's disease: cross-sectional and longitudinal analysis of the Dominantly Inherited Alzheimer Network observational study (DIAN-OBS).
Schultz SA, Liu L, Schultz AP, Fitzpatrick CD, Levin R, Bellier JP, Shirzadi Z, Joseph-Mathurin N, Chen CD, Benzinger TLS, Day GS, Farlow MR, Gordon BA, Hassenstab JJ, Jack CR Jr, Jucker M, Karch CM, Lee JH, Levin J, Perrin RJ, Schofield PR, Xiong C, Johnson KA, McDade E, Bateman RJ, Sperling RA, Selkoe DJ, Chhatwal JP; Dominantly Inherited Alzheimer Network. Schultz SA, et al. Lancet Neurol. 2024 Sep;23(9):913-924. doi: 10.1016/S1474-4422(24)00236-9. Epub 2024 Jul 26. Lancet Neurol. 2024. PMID: 39074479
Ubiquitin-Proteasome System in the Different Stages of Dominantly Inherited Alzheimer's Disease.
McDade E, Liu H, Bui Q, Hassenstab J, Gordon B, Benzinger T, Shen Y, Timsina J, Wang L, Sung YJ, Karch C, Renton A, Daniels A, Morris J, Xiong C, Ibanez L, Perrin R, Llibre-Guerra JJ, Day G, Supnet-Bell C, Xu X, Berman S, Chhatwal J, Ikeuchi T, Kasuga K, Niimi Y, Huey E, Schofield P, Brooks W, Ryan N, Jucker M, Laske C, Levin J, Vöglein J, Roh JH, Lopera F, Bateman R, Cruchaga C. McDade E, et al. Res Sq [Preprint]. 2024 Jul 23:rs.3.rs-4202125. doi: 10.21203/rs.3.rs-4202125/v1. Res Sq. 2024. PMID: 39108475 Free PMC article. Preprint.
15 Years of Longitudinal Genetic, Clinical, Cognitive, Imaging, and Biochemical Measures in DIAN.
Daniels AJ, McDade E, Llibre-Guerra JJ, Xiong C, Perrin RJ, Ibanez L, Supnet-Bell C, Cruchaga C, Goate A, Renton AE, Benzinger TLS, Gordon BA, Hassenstab J, Karch C, Popp B, Levey A, Morris J, Buckles V, Allegri RF, Chrem P, Berman SB, Chhatwal JP, Farlow MR, Fox NC, Day GS, Ikeuchi T, Jucker M, Lee JH, Levin J, Lopera F, Takada L, Sosa AL, Martins R, Mori H, Noble JM, Salloway S, Huey E, Rosa-Neto P, Sánchez-Valle R, Schofield PR, Roh JH, Bateman RJ; Dominantly Inherited Alzheimer Network. Daniels AJ, et al. medRxiv [Preprint]. 2024 Aug 9:2024.08.08.24311689. doi: 10.1101/2024.08.08.24311689. medRxiv. 2024. PMID: 39148846 Free PMC article. Preprint.
Longitudinal associations between exercise and biomarkers in autosomal dominant Alzheimer's disease.
Sewell KR, Doecke JD, Xiong C, Benzinger T, Masters CL, Laske C, Jucker M, Lopera F, Gordon BA, Llibre-Guerra J, Levin J, Huey ED, Hassenstab J, Schofield PR, Day GS, Fox NC, Chhatwal J, Ibanez L, Roh JH, Perrin R, Lee JH, Allegri RF, Supnet-Bell C, Berman SB, Daniels A, Noble J, Martins RN, Rainey-Smith S, Peiffer J, Gardener SL, Bateman RJ, Morris JC, McDade E, Erickson KI, Sohrabi HR, Brown BM; Dominantly Inherited Alzheimer's Network. Sewell KR, et al. Among authors: huey ed. Alzheimers Dement. 2024 Nov;20(11):7923-7939. doi: 10.1002/alz.14270. Epub 2024 Sep 26. Alzheimers Dement. 2024. PMID: 39324510 Free PMC article.
Comparative neurofilament light chain trajectories in CSF and plasma in autosomal dominant Alzheimer's disease.
Hofmann A, Häsler LM, Lambert M, Kaeser SA, Gräber-Sultan S, Obermüller U, Kuder-Buletta E, la Fougere C, Laske C, Vöglein J, Levin J, Fox NC, Ryan NS, Zetterberg H, Llibre-Guerra JJ, Perrin RJ, Ibanez L, Schofield PR, Brooks WS, Day GS, Farlow MR, Allegri RF, Chrem Mendez P, Ikeuchi T, Kasuga K, Lee JH, Roh JH, Mori H, Lopera F, Bateman RJ, McDade E, Gordon BA, Chhatwal JP, Jucker M, Schultz SA; Dominantly Inherited Alzheimer Network. Hofmann A, et al. Nat Commun. 2024 Nov 18;15(1):9982. doi: 10.1038/s41467-024-52937-8. Nat Commun. 2024. PMID: 39557867 Free PMC article.
Psychotic symptoms are associated with elevated tau PET signal in the amygdala independent of Alzheimer's disease clinical severity and amyloid burden.
Johnson AS, Ziaggi G, Smith AC, Houlihan H, Heuer LB, Guzmán DS, Okafor A, Huey ED, Talmasov D, Provenzano F, Kreisl WC, Lao PJ; Alzheimer’s Disease Neuroimaging Initiative. Johnson AS, et al. Among authors: huey ed. medRxiv [Preprint]. 2024 Jan 13:2024.01.12.24301221. doi: 10.1101/2024.01.12.24301221. medRxiv. 2024. PMID: 38260648 Free PMC article. Preprint.
Clinical application of plasma P-tau217 to assess eligibility for amyloid-lowering immunotherapy in memory clinic patients with early Alzheimer's disease.
Howe MD, Britton KJ, Joyce HE, Menard W, Emrani S, Kunicki ZJ, Faust MA, Dawson BC, Riddle MC, Huey ED, Janelidze S, Hansson O, Salloway SP. Howe MD, et al. Among authors: huey ed. Alzheimers Res Ther. 2024 Jul 6;16(1):154. doi: 10.1186/s13195-024-01521-9. Alzheimers Res Ther. 2024. PMID: 38971815 Free PMC article.
193 results