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126 results

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Page 1
Evaluation of long-acting cabotegravir safety and pharmacokinetics in pregnant women in eastern and southern Africa: a secondary analysis of HPTN 084.
Delany-Moretlwe S, Hanscom B, Guo X, Nkabiito C, Mandima P, Nahirya PN, Mpendo J, Bhondai-Mhuri M, Mgodi N, Berhanu R, Farrior J, Piwowar-Manning E, Ford SL, Hendrix CW, Rinehart AR, Rooney JF, Adeyeye A, Landovitz RJ, Cohen MS, Hosseinipour MC, Marzinke MA; HPTN 084 Study Team. Delany-Moretlwe S, et al. Among authors: piwowar manning e. J Int AIDS Soc. 2025 Jan;28(1):e26401. doi: 10.1002/jia2.26401. J Int AIDS Soc. 2025. PMID: 39748218 Free PMC article. Clinical Trial.
Safety, tolerability, pharmacokinetics, and neutralisation activities of the anti-HIV-1 monoclonal antibody PGT121.414.LS administered alone and in combination with VRC07-523LS in adults without HIV in the USA (HVTN 136/HPTN 092): a first-in-human, open-label, randomised controlled phase 1 trial.
Edupuganti S, Hurt CB, Stephenson KE, Huang Y, Paez CA, Yu C, Yen C, Hanscom B, He Z, Miner MD, Gamble T, Heptinstall J, Seaton KE, Domin E, Lin BC, McKee K, Doria-Rose N, Regenold S, Spiegel H, Anderson M, McClosky N, Zhang L, Piwowar-Manning E, Ackerman ME, Pensiero M, Dye BJ, Landovitz RJ, Mayer K, Siegel M, Sobieszczyk M, Walsh SR, Gama L, Barouch DH, Montefiori DC, Tomaras GD; HVTN 136/HPTN 092 Study Team. Edupuganti S, et al. Among authors: piwowar manning e. Lancet HIV. 2024 Dec 9:S2352-3018(24)00247-9. doi: 10.1016/S2352-3018(24)00247-9. Online ahead of print. Lancet HIV. 2024. PMID: 39667379
HIV DNA Levels in Persons Who Acquired HIV in the Setting of Long-Acting Cabotegravir for HIV Prevention: Analysis of Cases from HPTN 083 and 084.
Fogel JM, Persaud D, Piwowar-Manning E, Richardson P, Szewczyk J, Marzinke MA, Wang Z, Guo X, McCauley M, Farrior J, Tran HV, Ungsedhapand C, Mathew CA, Mpendo J, Rinehart AR, Rooney JF, Cohen MS, Hanscom B, Grinsztejn B, Hosseinipour MC, Delany-Moretlwe S, Landovitz RJ, Eshleman SH; HPTN 083 and HPTN 084 Study Teams. Fogel JM, et al. Among authors: piwowar manning e. AIDS Res Hum Retroviruses. 2024 Oct 28. doi: 10.1089/aid.2024.0049. Online ahead of print. AIDS Res Hum Retroviruses. 2024. PMID: 39466048
Pharmacologic evaluation of delayed long-acting cabotegravir administration among cisgender women in HPTN 084.
Marzinke MA, Han K, Hanscom B, Guo X, Piwowar-Manning E, Hendrix CW, Rose S, Spooner E, Mathew C, Innes S, Sekabira R, Mutambanengwe M, Rooney JF, Rinehart AR, Adeyeye A, Cohen MS, Hosseinipour M, Ford SL, Delany-Moretlwe S. Marzinke MA, et al. Among authors: piwowar manning e. Antimicrob Agents Chemother. 2024 Nov 6;68(11):e0099424. doi: 10.1128/aac.00994-24. Epub 2024 Sep 23. Antimicrob Agents Chemother. 2024. PMID: 39311597 Clinical Trial.
Ethnic identity and social support as mediators between childhood sexual abuse and depression among black men who have sex with men.
Boyd DT, Jones KV, Quinn CR, Hill M, Nelson LE, Beauchamp G, Emel L, Hightow-Weidman L, Shoptaw S, Magnus M, Piwowar-Manning E, Mayer KH, Fields SD, Wheeler DP, Dyer TV, Wilton L. Boyd DT, et al. Among authors: piwowar manning e. Child Abuse Negl. 2024 Nov;157:107064. doi: 10.1016/j.chiabu.2024.107064. Epub 2024 Sep 19. Child Abuse Negl. 2024. PMID: 39303435
Identification of antibody targets associated with lower HIV viral load and viremic control.
Grant-McAuley W, Morgenlander WR, Ruczinski I, Kammers K, Laeyendecker O, Hudelson SE, Thakar M, Piwowar-Manning E, Clarke W, Breaud A, Ayles H, Bock P, Moore A, Kosloff B, Shanaube K, Meehan SA, van Deventer A, Fidler S, Hayes R, Larman HB, Eshleman SH; HPTN 071 (PopART) Study Team. Grant-McAuley W, et al. Among authors: piwowar manning e. PLoS One. 2024 Sep 17;19(9):e0305976. doi: 10.1371/journal.pone.0305976. eCollection 2024. PLoS One. 2024. PMID: 39288118 Free PMC article. Clinical Trial.
Strengthening the Application of the DAIDS GCLP Guidelines: The Implementation of an Integrated Laboratory Oversight Framework.
Nguyen L, Leach A, Piwowar-Manning E, Marzinke M, Levesque A, Gregorio C, Skinner K, Towindo T, Hanes H, Sarpong K, Kasongo C, Samsunder N, Aldrovandi G, Ferbas KG, Engelbrecht A, Stirewalt M, Anyango E, Ubolyam S, Lankford-Turner P, Sarzotti-Kelsoe M. Nguyen L, et al. Among authors: piwowar manning e. AIDS Res Hum Retroviruses. 2024 Nov;40(11):622-630. doi: 10.1089/AID.2024.0042. Epub 2024 Sep 4. AIDS Res Hum Retroviruses. 2024. PMID: 39135473
Features of HIV Infection in the Context of Long-Acting Cabotegravir Preexposure Prophylaxis.
Landovitz RJ, Delany-Moretlwe S, Fogel JM, Marzinke MA, Piwowar-Manning E, Richardson P, Halvas EK, Mellors JW, Persaud D, Kofron R, McCauley M, Rose S, Rinehart AR, Rooney JF, Adeyeye A, Cohen MS, Donnell D, Hosseinipour MC, Grinsztejn B, Eshleman SH; HPTN 083 and 084 Study Teams. Landovitz RJ, et al. Among authors: piwowar manning e. N Engl J Med. 2024 Oct 3;391(13):1253-1256. doi: 10.1056/NEJMc2402088. Epub 2024 Jul 24. N Engl J Med. 2024. PMID: 39046350 Free PMC article. No abstract available.
Evaluation of Xpert point-of-care assays for detection of HIV infection in persons using long-acting cabotegravir for pre-exposure prophylaxis.
Fogel JM, Piwowar-Manning E, Moser A, Hill T, Ahmed S, Cummings V, Mostafa HH, Wang Z, Jennings A, Gallardo-Cartagena JA, Figueroa MI, St Clair M, Rinehart AR, Adeyeye A, Rooney JF, Cohen MS, Grinsztejn B, Landovitz RJ, Eshleman SH; HPTN 083 Study Team. Fogel JM, et al. Among authors: piwowar manning e. Microbiol Spectr. 2024 Jul 9;12(8):e0030724. doi: 10.1128/spectrum.00307-24. Online ahead of print. Microbiol Spectr. 2024. PMID: 38980027 Free PMC article.
Safety and pharmacokinetics of VRC07-523LS administered via different routes and doses (HVTN 127/HPTN 087): A Phase I randomized clinical trial.
Walsh SR, Gay CL, Karuna ST, Hyrien O, Skalland T, Mayer KH, Sobieszczyk ME, Baden LR, Goepfert PA, Del Rio C, Pantaleo G, Andrew P, Karg C, He Z, Lu H, Paez CA, Baumblatt JAG, Polakowski LL, Chege W, Anderson MA, Janto S, Han X, Huang Y, Dumond J, Ackerman ME, McDermott AB, Flach B, Piwowar-Manning E, Seaton K, Tomaras GD, Montefiori DC, Gama L, Mascola JR; HVTN 127/HPTN 087 Study Team. Walsh SR, et al. Among authors: piwowar manning e. PLoS Med. 2024 Jun 24;21(6):e1004329. doi: 10.1371/journal.pmed.1004329. eCollection 2024 Jun. PLoS Med. 2024. PMID: 38913710 Free PMC article. Clinical Trial.
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