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531 results

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An Acetylcholine M1 Receptor-Positive Allosteric Modulator (TAK-071) in Parkinson Disease With Cognitive Impairment: A Phase 2 Randomized Clinical Trial.
Shanbhag NM, Padmanabhan JL, Zhang Z, Harel BT, Jia H, Kangarloo T, Yin W, Dowling AV, Laurenza A, Khudyakov P, Galinsky K, Latzman RD, Simuni T, Weintraub D, Horak FB, Lustig C, Maruff P, Simen AA. Shanbhag NM, et al. Among authors: maruff p. JAMA Neurol. 2025 Jan 6. doi: 10.1001/jamaneurol.2024.4519. Online ahead of print. JAMA Neurol. 2025. PMID: 39761063
Alzheimer's disease drug development in an evolving therapeutic landscape.
Weninger S, Irizarry MC, Fleisher AS, León T, Maruff P, Miller DS, Seleri S, Carrillo MC, Weber CJ. Weninger S, et al. Among authors: maruff p. Alzheimers Dement (N Y). 2024 Nov 30;10(4):e70015. doi: 10.1002/trc2.70015. eCollection 2024 Oct-Dec. Alzheimers Dement (N Y). 2024. PMID: 39748838 Free PMC article.
Evaluation of effect of cooled haemodialysis on cognition in patients with end-stage kidney disease (ECHECKED) feasibility randomised controlled trial results.
Dasgupta I, Odudu A, Baharani J, Fergusson N, Griffiths H, Harrison J, Hameed A, Maruff P, Ryan L, Thomas N, Woodhall G, Tadros G. Dasgupta I, et al. Among authors: maruff p. BMC Nephrol. 2024 Dec 19;25(1):466. doi: 10.1186/s12882-024-03883-6. BMC Nephrol. 2024. PMID: 39702060 Free PMC article. Clinical Trial.
Effect of Esketamine Nasal Spray on Cognition in Patients With Treatment-Resistant Depression: Results From Four Phase 3 Studies.
Morrison RL, Singh J, Daly E, Fedgchin M, Ochs-Ross R, Karcher K, Lane R, Cooper K, Sanacora G, Maruff P, Drevets WC. Morrison RL, et al. Among authors: maruff p. Int J Neuropsychopharmacol. 2024 Nov 1;27(11):pyae046. doi: 10.1093/ijnp/pyae046. Int J Neuropsychopharmacol. 2024. PMID: 39514643 Free PMC article. Clinical Trial.
Deferiprone in Alzheimer Disease: A Randomized Clinical Trial.
Ayton S, Barton D, Brew B, Brodtmann A, Clarnette R, Desmond P, Devos D, Ellis KA, Fazlollahi A, Fradette C, Goh AMY, Kalinowski P, Kyndt C, Lai R, Lim YY, Maruff P, O'Brien TJ, Rowe C, Salvado O, Schofield PW, Spino M, Tricta F, Wagen A, Williams R, Woodward M, Bush AI. Ayton S, et al. Among authors: maruff p. JAMA Neurol. 2024 Nov 4:e243733. doi: 10.1001/jamaneurol.2024.3733. Online ahead of print. JAMA Neurol. 2024. PMID: 39495531
Cognitive effects, pharmacokinetics, and safety of zuranolone administered alone or with alprazolam or ethanol in healthy adults in a phase 1 trial.
Dunbar J, Walling DP, Hassman HA, Jain R, Czysz A, Nandy I, Ona V, Moseley MK, Levin S, Maruff P. Dunbar J, et al. Among authors: maruff p. J Psychopharmacol. 2024 Dec;38(12):1122-1136. doi: 10.1177/02698811241282777. Epub 2024 Oct 11. J Psychopharmacol. 2024. PMID: 39394685 Free PMC article. Clinical Trial.
531 results