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Amyloid-β predominant Alzheimer's disease neuropathologic change.
Kovacs GG, Katsumata Y, Wu X, Aung KZ, Fardo DW, Forrest SL; Alzheimer's Disease Genetics Consortium; Nelson PT. Kovacs GG, et al. Brain. 2024 Oct 17:awae325. doi: 10.1093/brain/awae325. Online ahead of print. Brain. 2024. PMID: 39417691
The impact of astrocytic NF-κB on healthy and Alzheimer's disease brains.
Jong Huat T, Camats-Perna J, Newcombe EA, Onraet T, Campbell D, Sucic JT, Martini A, Forner S, Mirzaei M, Poon W, LaFerla FM, Medeiros R. Jong Huat T, et al. Among authors: laferla fm. Sci Rep. 2024 Jun 21;14(1):14305. doi: 10.1038/s41598-024-65248-1. Sci Rep. 2024. PMID: 38906984 Free PMC article.
APOE Christchurch enhances a disease-associated microglial response to plaque but suppresses response to tau pathology.
Tran KM, Kwang N, Gomez-Arboledas A, Kawauchi S, Mar C, Chao D, Da Cunha C, Wang S, Collins S, Walker A, Shi KX, Alcantara JA, Neumann J, Tenner AJ, LaFerla FM, Hohsfield LA, Swarup V, MacGregor GR, Green KN. Tran KM, et al. Among authors: laferla fm. bioRxiv [Preprint]. 2024 Jun 4:2024.06.03.597211. doi: 10.1101/2024.06.03.597211. bioRxiv. 2024. PMID: 38895362 Free PMC article. Preprint.
Sex-specific associations between AD genotype and the microbiome of human amyloid beta knock-in (hAβ-KI) mice.
Dunham SJB, Avelar-Barragan J, Rothman JA, Adams ED, Faraci G, Forner S, Kawauchi S, Tenner AJ, Green KN, LaFerla FM, MacGregor GR, Mapstone M, Whiteson KL. Dunham SJB, et al. Among authors: laferla fm. Alzheimers Dement. 2024 Jul;20(7):4935-4950. doi: 10.1002/alz.13794. Epub 2024 Apr 4. Alzheimers Dement. 2024. PMID: 38572865 Free PMC article.
The Abca7V1613M variant reduces Aβ generation, plaque load, and neuronal damage.
Butler CA, Mendoza Arvilla A, Milinkeviciute G, Da Cunha C, Kawauchi S, Rezaie N, Liang HY, Javonillo D, Thach A, Wang S, Collins S, Walker A, Shi KX, Neumann J, Gomez-Arboledas A, Henningfield CM, Hohsfield LA, Mapstone M, Tenner AJ, LaFerla FM, Mortazavi A, MacGregor GR, Green KN. Butler CA, et al. Among authors: laferla fm. Alzheimers Dement. 2024 Jul;20(7):4914-4934. doi: 10.1002/alz.13783. Epub 2024 Mar 20. Alzheimers Dement. 2024. PMID: 38506634 Free PMC article.
BIN1K358R suppresses glial response to plaques in mouse model of Alzheimer's disease.
Garcia-Agudo LF, Shi Z, Smith IF, Kramár EA, Tran K, Kawauchi S, Wang S, Collins S, Walker A, Shi KX, Neumann J, Liang HY, Da Cunha C, Milinkeviciute G, Morabito S, Miyoshi E, Rezaie N, Gomez-Arboledas A, Arvilla AM, Ghaemi DI, Tenner AJ, LaFerla FM, Wood MA, Mortazavi A, Swarup V, MacGregor GR, Green KN. Garcia-Agudo LF, et al. Among authors: laferla fm. Alzheimers Dement. 2024 Apr;20(4):2922-2942. doi: 10.1002/alz.13767. Epub 2024 Mar 9. Alzheimers Dement. 2024. PMID: 38460121 Free PMC article.
Genetic diversity promotes resilience in a mouse model of Alzheimer's disease.
Soni N, Hohsfield LA, Tran KM, Kawauchi S, Walker A, Javonillo D, Phan J, Matheos D, Da Cunha C, Uyar A, Milinkeviciute G, Gomez-Arboledas A, Tran K, Kaczorowski CC, Wood MA, Tenner AJ, LaFerla FM, Carter GW, Mortazavi A, Swarup V, MacGregor GR, Green KN. Soni N, et al. Among authors: laferla fm. Alzheimers Dement. 2024 Apr;20(4):2794-2816. doi: 10.1002/alz.13753. Epub 2024 Mar 1. Alzheimers Dement. 2024. PMID: 38426371 Free PMC article.
Whole genome-wide sequence analysis of long-lived families (Long-Life Family Study) identifies MTUS2 gene associated with late-onset Alzheimer's disease.
Xicota L, Cosentino S, Vardarajan B, Mayeux R, Perls TT, Andersen SL, Zmuda JM, Thyagarajan B, Yashin A, Wojczynski MK, Krinsky-McHale S, Handen BL, Christian BT, Head E, Mapstone ME, Schupf N, Lee JH, Barral S; Long‐Life Family Study (LLFS); Alzheimer's Disease Genetic Consortium (ADGC); Alzheimer's Biomarkers Consortium‐Down Syndrome (ABC‐DS). Xicota L, et al. Alzheimers Dement. 2024 Apr;20(4):2670-2679. doi: 10.1002/alz.13718. Epub 2024 Feb 21. Alzheimers Dement. 2024. PMID: 38380866 Free PMC article.
249 results