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Page 1
Detection of H3F3A K27M or BRAF V600E in liquid biopsies of brain tumor patients as diagnostic and monitoring biomarker: impact of tumor localization and sampling method.
Madlener S, Stepien N, Senfter D, Mayr L, Laemmerer A, Hedrich C, Baumgartner A, Lötsch-Gojo D, Sterba J, Pokorna P, Kiesel B, Widhalm G, Eckert F, Preusser M, Rössler K, Azizi A, Peyrl A, Czech T, Haberler C, Slavc I, Kasprian G, Dorfer C, Furtner J, Gojo J. Madlener S, et al. Among authors: pokorna p. Acta Neuropathol. 2025 Jan 3;149(1):5. doi: 10.1007/s00401-024-02842-7. Acta Neuropathol. 2025. PMID: 39751690 Free PMC article.
Real-World Performance of Integrative Clinical Genomics in Pediatric Precision Oncology.
Pokorna P, Palova H, Adamcova S, Jugas R, Al Tukmachi D, Kyr M, Knoflickova D, Kozelkova K, Bystry V, Mejstrikova S, Merta T, Trachtova K, Podlipna E, Mudry P, Pavelka Z, Bajciova V, Tinka P, Jarosova M, Catela Ivkovic T, Madlener S, Pal K, Stepien N, Mayr L, Tichy B, Drabova K, Jezova M, Kozakova S, Vanackova J, Radova L, Steininger K, Haberler C, Gojo J, Sterba J, Slaby O. Pokorna P, et al. Lab Invest. 2024 Dec;104(12):102161. doi: 10.1016/j.labinv.2024.102161. Epub 2024 Oct 21. Lab Invest. 2024. PMID: 39442669 Free article.
PredictONCO: a web tool supporting decision-making in precision oncology by extending the bioinformatics predictions with advanced computing and machine learning.
Stourac J, Borko S, Khan RT, Pokorna P, Dobias A, Planas-Iglesias J, Mazurenko S, Pinto G, Szotkowska V, Sterba J, Slaby O, Damborsky J, Bednar D. Stourac J, et al. Among authors: pokorna p. Brief Bioinform. 2023 Nov 22;25(1):bbad441. doi: 10.1093/bib/bbad441. Brief Bioinform. 2023. PMID: 38066711 Free PMC article.
Targeted treatment of severe vascular malformations harboring PIK3CA and TEK mutations with alpelisib is highly effective with limited toxicity.
Sterba M, Pokorna P, Faberova R, Pinkova B, Skotakova J, Seehofnerova A, Blatny J, Janigova L, Koskova O, Palova H, Mahdal M, Pazourek L, Jabandziev P, Slaby O, Mudry P, Sterba J. Sterba M, et al. Among authors: pokorna p. Sci Rep. 2023 Jun 28;13(1):10499. doi: 10.1038/s41598-023-37468-4. Sci Rep. 2023. PMID: 37380669 Free PMC article.
Tazemetostat in the therapy of pediatric INI1-negative malignant rhabdoid tumors.
Vejmelkova K, Pokorna P, Noskova K, Faustmannova A, Drabova K, Pavelka Z, Bajciova V, Broz M, Tinka P, Jezova M, Palova H, Kren L, Valik D, Slaby O, Sterba J. Vejmelkova K, et al. Among authors: pokorna p. Sci Rep. 2023 Dec 7;13(1):21623. doi: 10.1038/s41598-023-48774-2. Sci Rep. 2023. PMID: 38062114 Free PMC article.
Analysis of mutations in precision oncology using the automated, accurate, and user-friendly web tool PredictONCO.
Khan RT, Pokorna P, Stourac J, Borko S, Dobias A, Planas-Iglesias J, Mazurenko S, Arefiev I, Pinto G, Szotkowska V, Sterba J, Damborsky J, Slaby O, Bednar D. Khan RT, et al. Among authors: pokorna p. Comput Struct Biotechnol J. 2024 Nov 14;24:734-738. doi: 10.1016/j.csbj.2024.11.026. eCollection 2024 Dec. Comput Struct Biotechnol J. 2024. PMID: 39687752 Free PMC article.
A computational workflow for analysis of missense mutations in precision oncology.
Khan RT, Pokorna P, Stourac J, Borko S, Arefiev I, Planas-Iglesias J, Dobias A, Pinto G, Szotkowska V, Sterba J, Slaby O, Damborsky J, Mazurenko S, Bednar D. Khan RT, et al. Among authors: pokorna p. J Cheminform. 2024 Jul 29;16(1):86. doi: 10.1186/s13321-024-00876-3. J Cheminform. 2024. PMID: 39075588 Free PMC article.
Personalized dendritic cell vaccine in multimodal individualized combination therapy improves survival in high-risk pediatric cancer patients.
Kyr M, Mudry P, Polaskova K, Dubska LZ, Demlova R, Kubatova J, Hlavackova E, Pilatova KC, Mazanek P, Vejmelkova K, Dusek V, Tinka P, Balaz M, Merta T, Kuttnerova Z, Turekova T, Pavelka Z, Pokorna P, Palova H, Mlnarikova M, Jezova M, Kellnerova R, Kozakova S, Slaby O, Valik D, Sterba J. Kyr M, et al. Among authors: pokorna p. Int J Cancer. 2024 Oct 15;155(8):1443-1454. doi: 10.1002/ijc.35062. Epub 2024 Jul 3. Int J Cancer. 2024. PMID: 38958237
95 results