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Utilization of primary tumor samples for cancer neoantigen discovery.
Leko V, Groh E, Levi ST, Copeland AR, White BS, Gasmi B, Li Y, Hill V, Gurusamy D, Levin N, Kim SP, Sindiri S, Gartner JJ, Prickett TD, Parkhust M, Lowery FJ, Goff SL, Rosenberg SA, Robbins P. Leko V, et al. Among authors: gurusamy d. J Immunother Cancer. 2025 Jan 11;13(1):e010993. doi: 10.1136/jitc-2024-010993. J Immunother Cancer. 2025. PMID: 39800378 Free PMC article.
Endonuclease G promotes hepatic mitochondrial respiration by selectively increasing mitochondrial tRNAThr production.
Xu X, Penjweini R, Székvölgyi L, Karányi Z, Heckel AM, Gurusamy D, Varga D, Yang S, Brown AL, Cui W, Park J, Nagy D, Podszun MC, Yang S, Singh K, Ashcroft SP, Kim J, Kim MK, Tarassov I, Zhu J, Philp A, Rotman Y, Knutson JR, Entelis N, Chung JH. Xu X, et al. Among authors: gurusamy d. Proc Natl Acad Sci U S A. 2025 Jan 7;122(1):e2411298122. doi: 10.1073/pnas.2411298122. Epub 2025 Jan 3. Proc Natl Acad Sci U S A. 2025. PMID: 39752519 Free PMC article.
Internal checkpoint regulates T cell neoantigen reactivity and susceptibility to PD1 blockade.
Palmer DC, Webber BR, Patel Y, Johnson MJ, Kariya CM, Lahr WS, Parkhurst MR, Gartner JJ, Prickett TD, Lowery FJ, Kishton RJ, Gurusamy D, Franco Z, Vodnala SK, Diers MD, Wolf NK, Slipek NJ, McKenna DH, Sumstad D, Viney L, Henley T, Bürckstümmer T, Baker O, Hu Y, Yan C, Meerzaman D, Padhan K, Lo W, Malekzadeh P, Jia L, Deniger DC, Patel SJ, Robbins PF, McIvor RS, Choudhry M, Rosenberg SA, Moriarity BS, Restifo NP. Palmer DC, et al. Among authors: gurusamy d. Med. 2022 Oct 14;3(10):682-704.e8. doi: 10.1016/j.medj.2022.07.008. Epub 2022 Aug 24. Med. 2022. PMID: 36007524 Free PMC article.
Cancer genes disfavoring T cell immunity identified via integrated systems approach.
Kishton RJ, Patel SJ, Decker AE, Vodnala SK, Cam M, Yamamoto TN, Patel Y, Sukumar M, Yu Z, Ji M, Henning AN, Gurusamy D, Palmer DC, Stefanescu RA, Girvin AT, Lo W, Pasetto A, Malekzadeh P, Deniger DC, Wood KC, Sanjana NE, Restifo NP. Kishton RJ, et al. Among authors: gurusamy d. Cell Rep. 2022 Aug 2;40(5):111153. doi: 10.1016/j.celrep.2022.111153. Cell Rep. 2022. PMID: 35926468 Free PMC article.
44 results