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A high affinity monoclonal antibody against HLA-E-VL9 enhances natural killer cell anti-tumor killing.
Hwang JK, Marston DJ, Wrapp D, Li D, Tuyishime M, Brackenridge S, Rhodes B, Quastel M, Kapingidza AB, Gater J, Harner A, Wang Y, Rountree W, Ferrari G, Borrow P, McMichael AJ, Gillespie GM, Haynes BF, Azoitei ML. Hwang JK, et al. Among authors: gillespie gm. bioRxiv [Preprint]. 2024 Jul 11:2024.07.08.602401. doi: 10.1101/2024.07.08.602401. bioRxiv. 2024. PMID: 39026709 Free PMC article. Preprint.
Mucosal signatures of pathogenic T cells in HLA-B*27+ anterior uveitis and axial spondyloarthritis.
Paley MA, Yang X, Hassman LM, Penkava F, Garner LI, Paley GL, Linskey N, Agnew R, Arantes de Faria PH, Feng A, Li SY, Simone D, Roberson ED, Ruzycki PA, Esaulova E, Laurent J, Feigl-Lenzen L, Springer LE, Liu C, Gillespie GM, Bowness P, Garcia KC, Yokoyama WM. Paley MA, et al. Among authors: gillespie gm. JCI Insight. 2024 Jul 18;9(16):e174776. doi: 10.1172/jci.insight.174776. JCI Insight. 2024. PMID: 39024572 Free PMC article.
HLA-E-restricted SARS-CoV-2-specific T cells from convalescent COVID-19 patients suppress virus replication despite HLA class Ia down-regulation.
Yang H, Sun H, Brackenridge S, Zhuang X, Wing PAC, Quastel M, Walters L, Garner L, Wang B, Yao X, Felce SL, Peng Y, Moore S, Peeters BWA, Rei M, Canto Gomes J, Tomas A, Davidson A, Semple MG, Turtle LCW, Openshaw PJM, Baillie JK, Mentzer AJ, Klenerman P; ISARIC4C Investigators; Borrow P, Dong T, McKeating JA, Gillespie GM, McMichael AJ. Yang H, et al. Among authors: gillespie gm. Sci Immunol. 2023 Jun 30;8(84):eabl8881. doi: 10.1126/sciimmunol.abl8881. Epub 2023 Jun 30. Sci Immunol. 2023. PMID: 37390223
HLA class I signal peptide polymorphism determines the level of CD94/NKG2-HLA-E-mediated regulation of effector cell responses.
Lin Z, Bashirova AA, Viard M, Garner L, Quastel M, Beiersdorfer M, Kasprzak WK, Akdag M, Yuki Y, Ojeda P, Das S, Andresson T, Naranbhai V, Horowitz A, McMichael AJ, Hoelzemer A, Gillespie GM, Garcia-Beltran WF, Carrington M. Lin Z, et al. Among authors: gillespie gm. Nat Immunol. 2023 Jul;24(7):1087-1097. doi: 10.1038/s41590-023-01523-z. Epub 2023 Jun 1. Nat Immunol. 2023. PMID: 37264229 Free PMC article.
Intracellular trafficking of HLA-E and its regulation.
He W, Gea-Mallorquí E, Colin-York H, Fritzsche M, Gillespie GM, Brackenridge S, Borrow P, McMichael AJ. He W, et al. Among authors: gillespie gm. J Exp Med. 2023 Aug 7;220(8):e20221941. doi: 10.1084/jem.20221941. Epub 2023 May 4. J Exp Med. 2023. PMID: 37140910 Free PMC article.
64 results