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Page 1
Exploring the chemical space of orally bioavailable PROTACs.
Apprato G, Poongavanam V, Garcia Jimenez D, Atilaw Y, Erdelyi M, Ermondi G, Caron G, Kihlberg J. Apprato G, et al. Among authors: kihlberg j. Drug Discov Today. 2024 Apr;29(4):103917. doi: 10.1016/j.drudis.2024.103917. Epub 2024 Feb 14. Drug Discov Today. 2024. PMID: 38360147 Free article. Review.
Design of Drug Efficacy Guided by Free Energy Simulations of the β2 -Adrenoceptor.
Panel N, Vo DD, Kahlous NA, Hübner H, Tiedt S, Matricon P, Pacalon J, Fleetwood O, Kampen S, Luttens A, Delemotte L, Kihlberg J, Gmeiner P, Carlsson J. Panel N, et al. Among authors: kihlberg j. Angew Chem Int Ed Engl. 2023 May 22;62(22):e202218959. doi: 10.1002/anie.202218959. Epub 2023 Apr 20. Angew Chem Int Ed Engl. 2023. PMID: 36914577
Therapy targeting antigen-specific T cells by a peptide-based tolerizing vaccine against autoimmune arthritis.
Urbonaviciute V, Romero-Castillo L, Xu B, Luo H, Schneider N, Weisse S, Do NN, Oliveira-Coelho A, Fernandez Lahore G, Li T, Sabatier P, Beusch CM, Viljanen J, Zubarev RA, Kihlberg J, Bäcklund J, Burkhardt H, Holmdahl R. Urbonaviciute V, et al. Among authors: kihlberg j. Proc Natl Acad Sci U S A. 2023 Jun 20;120(25):e2218668120. doi: 10.1073/pnas.2218668120. Epub 2023 Jun 12. Proc Natl Acad Sci U S A. 2023. PMID: 37307481 Free PMC article.
Autoantibodies to Disease-Related Proteins in Joints as Novel Biomarkers for the Diagnosis of Rheumatoid Arthritis.
Lönnblom E, Leu Agelii M, Sareila O, Cheng L, Xu B, Viljanen J, Hafström I, Andersson MLE, Bergström G, Hultgård Ekwall AK, Rudin A, Kastbom A, Sjöwall C, Jacobsson LTH, Kihlberg J, Gjertsson I, Holmdahl R. Lönnblom E, et al. Among authors: kihlberg j. Arthritis Rheumatol. 2023 Jul;75(7):1110-1119. doi: 10.1002/art.42463. Epub 2023 Apr 27. Arthritis Rheumatol. 2023. PMID: 36718635 Free article.
Autoantibodies to joint-related peptides as predictive markers in early rheumatoid arthritis.
Agelii ML, Sareila O, Lönnblom E, Cheng L, Forslind K, Hafström I, Andersson M, Kastbom A, Sjöwall C, Jacobsson LTH, Kihlberg J, Holmdahl R, Gjertsson I. Agelii ML, et al. Among authors: kihlberg j. Rheumatology (Oxford). 2024 Jul 30:keae382. doi: 10.1093/rheumatology/keae382. Online ahead of print. Rheumatology (Oxford). 2024. PMID: 39078716
Impact of Linker Composition on VHL PROTAC Cell Permeability.
Abeje YE, Wieske LHE, Poongavanam V, Maassen S, Atilaw Y, Cromm P, Lehmann L, Erdelyi M, Meibom D, Kihlberg J. Abeje YE, et al. Among authors: kihlberg j. J Med Chem. 2025 Jan 9;68(1):638-657. doi: 10.1021/acs.jmedchem.4c02492. Epub 2024 Dec 18. J Med Chem. 2025. PMID: 39693386 Free PMC article.
207 results