Yang W - Search Results

1

Lanosterol 14α-Demethylase (CYP51)/Heat Shock Protein 90 (Hsp90) Dual Inhibitors for the Treatment of Invasive Candidiasis.

Zhang M, Yang W, Liu N, Tu J, Lin J, Dong G, Zhao D, Sheng C. Zhang M, et al. Among authors: yang w. J Med Chem. 2025 Jan 23;68(2):1668-1681. doi: 10.1021/acs.jmedchem.4c02305. Epub 2025 Jan 4. J Med Chem. 2025. PMID: 39754582

2

Discovery of Novel Sertraline Derivatives as Potent Anti-Cryptococcus Agents.

Li W, Yun Z, Ji C, Tu J, Yang W, Li J, Liu N, Sheng C. Li W, et al. Among authors: yang w. J Med Chem. 2022 May 12;65(9):6541-6554. doi: 10.1021/acs.jmedchem.1c01845. Epub 2022 Mar 6. J Med Chem. 2022. PMID: 35253435

3

Discovery of BRD4-HDAC Dual Inhibitors with Improved Fungal Selectivity and Potent Synergistic Antifungal Activity against Fluconazole-Resistant Candida albicans.

Li Z, Huang Y, Tu J, Yang W, Liu N, Wang W, Sheng C. Li Z, et al. Among authors: yang w. J Med Chem. 2023 Apr 27;66(8):5950-5964. doi: 10.1021/acs.jmedchem.3c00165. Epub 2023 Apr 10. J Med Chem. 2023. PMID: 37037787

4

Discovery of Pyrazolone Carbothioamide Derivatives as Inhibitors of the Pdr1-KIX Interaction for Combinational Treatment of Azole-Resistant Candidiasis.

Wang Q, Tu J, Yang W, Liang T, Liu N, Sheng C. Wang Q, et al. Among authors: yang w. J Med Chem. 2023 Sep 14;66(17):11893-11904. doi: 10.1021/acs.jmedchem.3c00488. Epub 2023 Aug 16. J Med Chem. 2023. PMID: 37584282

5

Discovery of New Tricyclic Oxime Sampangine Derivatives as Potent Antifungal Agents for the Treatment of Cryptococcosis and Candidiasis.

Yang W, Liu R, Li Z, Tu J, Xu D, Liu N, Sheng C. Yang W, et al. J Med Chem. 2024 Mar 28;67(6):4726-4738. doi: 10.1021/acs.jmedchem.3c02331. Epub 2024 Mar 15. J Med Chem. 2024. PMID: 38489247

6

Discovery of new fungal jumonji H3K27 demethylase inhibitors for the treatment of Cryptococcus neoformans and Candida auris infections.

Liu X, Li W, Liu Y, Wang X, Shi Q, Yang W, Tu J, Wang Y, Sheng C, Liu N. Liu X, et al. Among authors: yang w. Eur J Med Chem. 2025 Jan 5;281:117028. doi: 10.1016/j.ejmech.2024.117028. Epub 2024 Nov 6. Eur J Med Chem. 2025. PMID: 39536495

7

Discovery of Piperidol Derivatives for Combinational Treatment of Azole-Resistant Candidiasis.

Yang W, Tu J, Ji C, Li Z, Han G, Liu N, Li J, Sheng C. Yang W, et al. ACS Infect Dis. 2021 Mar 12;7(3):650-660. doi: 10.1021/acsinfecdis.0c00849. Epub 2021 Feb 16. ACS Infect Dis. 2021. PMID: 33593060

8

Role of Azole Drugs in Promoting Fungal Cell Autophagy Revealed by an NIR Fluorescence-Based Theranostic Probe.

Yang W, Zhang Y, Teng H, Liu N, Sheng C, Guo Y. Yang W, et al. Anal Chem. 2022 May 17;94(19):7092-7099. doi: 10.1021/acs.analchem.2c00859. Epub 2022 May 3. Anal Chem. 2022. PMID: 35503259

9

Jumonji Histone Demethylase Inhibitor JIB-04 as a Broad-Spectrum Antifungal Agent.

Wang T, Yang W, Liu Y, Li W, Wang Y, Liu N, Sheng C. Wang T, et al. Among authors: yang w. ACS Infect Dis. 2022 Jul 8;8(7):1316-1323. doi: 10.1021/acsinfecdis.2c00096. Epub 2022 Jun 12. ACS Infect Dis. 2022. PMID: 35695031

10

Small molecules for combating multidrug-resistant superbug Candida auris infections.

Tu J, Liu N, Huang Y, Yang W, Sheng C. Tu J, et al. Among authors: yang w. Acta Pharm Sin B. 2022 Nov;12(11):4056-4074. doi: 10.1016/j.apsb.2022.08.001. Epub 2022 Aug 12. Acta Pharm Sin B. 2022. PMID: 36386475 Free PMC article. Review.

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