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Page 1
Structure-Based Design and Evaluation of Reversible KRAS G13D Inhibitors.
Nilewski C, Labadie S, Wei B, Malhotra S, Do S, Gazzard L, Liu L, Shao C, Murray J, Izrayelit Y, Gustafson A, Endres NF, Ma F, Ye X, Zou J, Evangelista M. Nilewski C, et al. Among authors: endres nf. ACS Med Chem Lett. 2023 Dec 6;15(1):21-28. doi: 10.1021/acsmedchemlett.3c00478. eCollection 2024 Jan 11. ACS Med Chem Lett. 2023. PMID: 38229748 Free PMC article.
Discovery of GDC-0077 (Inavolisib), a Highly Selective Inhibitor and Degrader of Mutant PI3Kα.
Hanan EJ, Braun MG, Heald RA, MacLeod C, Chan C, Clausen S, Edgar KA, Eigenbrot C, Elliott R, Endres N, Friedman LS, Gogol E, Gu XH, Thibodeau RH, Jackson PS, Kiefer JR, Knight JD, Nannini M, Narukulla R, Pace A, Pang J, Purkey HE, Salphati L, Sampath D, Schmidt S, Sideris S, Song K, Sujatha-Bhaskar S, Ultsch M, Wallweber H, Xin J, Yeap S, Young A, Zhong Y, Staben ST. Hanan EJ, et al. J Med Chem. 2022 Dec 22;65(24):16589-16621. doi: 10.1021/acs.jmedchem.2c01422. Epub 2022 Dec 1. J Med Chem. 2022. PMID: 36455032
Architecture and membrane interactions of the EGF receptor.
Arkhipov A, Shan Y, Das R, Endres NF, Eastwood MP, Wemmer DE, Kuriyan J, Shaw DE. Arkhipov A, et al. Among authors: endres nf. Cell. 2013 Jan 31;152(3):557-69. doi: 10.1016/j.cell.2012.12.030. Cell. 2013. PMID: 23374350 Free PMC article.
Regulation of the catalytic activity of the EGF receptor.
Endres NF, Engel K, Das R, Kovacs E, Kuriyan J. Endres NF, et al. Curr Opin Struct Biol. 2011 Dec;21(6):777-84. doi: 10.1016/j.sbi.2011.07.007. Epub 2011 Aug 23. Curr Opin Struct Biol. 2011. PMID: 21868214 Free PMC article. Review.
15 results