Wang H - Search Results

1

Discovery of Potent and Selective CDK4/6 Inhibitors for the Treatment of Chemotherapy-Induced Myelosuppression.

Shi W, Wang R, Qian J, Wang L, Li Y, Mi Y, Jia Z, Pan M, Zhang X, Ye W, Xiong F, Hu X, Wang H. Shi W, et al. Among authors: wang h, wang l, wang r. J Med Chem. 2025 Jan 23;68(2):1446-1472. doi: 10.1021/acs.jmedchem.4c02080. Epub 2025 Jan 6. J Med Chem. 2025. PMID: 39760276

2

Synthesis and biological evaluation of clovamide analogues as potent anti-neuroinflammatory agents in vitro and in vivo.

Hu XL, Lin J, Lv XY, Feng JH, Zhang XQ, Wang H, Ye WC. Hu XL, et al. Among authors: wang h. Eur J Med Chem. 2018 May 10;151:261-271. doi: 10.1016/j.ejmech.2018.03.081. Epub 2018 Apr 1. Eur J Med Chem. 2018. PMID: 29626798

3

Optimization of N-Phenylpropenoyl-l-amino Acids as Potent and Selective Inducible Nitric Oxide Synthase Inhibitors for Parkinson's Disease.

Hu XL, Lv XY, Wang R, Long H, Feng JH, Wang BL, Shen W, Liu H, Xiong F, Zhang XQ, Ye WC, Wang H. Hu XL, et al. Among authors: wang h, wang r, wang bl. J Med Chem. 2021 Jun 10;64(11):7760-7777. doi: 10.1021/acs.jmedchem.1c00578. Epub 2021 May 21. J Med Chem. 2021. PMID: 34019417

4

Discovery of Novel Apigenin-Piperazine Hybrids as Potent and Selective Poly (ADP-Ribose) Polymerase-1 (PARP-1) Inhibitors for the Treatment of Cancer.

Long H, Hu X, Wang B, Wang Q, Wang R, Liu S, Xiong F, Jiang Z, Zhang XQ, Ye WC, Wang H. Long H, et al. Among authors: wang h, wang b, wang r, wang q. J Med Chem. 2021 Aug 26;64(16):12089-12108. doi: 10.1021/acs.jmedchem.1c00735. Epub 2021 Aug 18. J Med Chem. 2021. PMID: 34404206

5

Stereoisomers of Schisandrin B Are Potent ATP Competitive GSK-3β Inhibitors with Neuroprotective Effects against Alzheimer's Disease: Stereochemistry and Biological Activity.

Hu XL, Guo C, Hou JQ, Feng JH, Zhang XQ, Xiong F, Ye WC, Wang H. Hu XL, et al. Among authors: wang h. ACS Chem Neurosci. 2019 Feb 20;10(2):996-1007. doi: 10.1021/acschemneuro.8b00252. Epub 2018 Jul 6. ACS Chem Neurosci. 2019. PMID: 29944335

6

Identification of amentoflavone as a potent highly selective PARP-1 inhibitor and its potentiation on carboplatin in human non-small cell lung cancer.

Hu XL, Feng JH, Pham TA, Ma HY, Ma MX, Song R, Shen W, Xiong F, Zhang XQ, Ye WC, Wang H. Hu XL, et al. Among authors: wang h. Phytomedicine. 2018 Nov 15;50:88-98. doi: 10.1016/j.phymed.2018.09.012. Epub 2018 Sep 5. Phytomedicine. 2018. PMID: 30466996

7

Synthesis and biological evaluation of clovamide analogues with catechol functionality as potent Parkinson's disease agents in vitro and in vivo.

Feng JH, Hu XL, Lv XY, Wang BL, Lin J, Zhang XQ, Ye WC, Xiong F, Wang H. Feng JH, et al. Among authors: wang h, wang bl. Bioorg Med Chem Lett. 2019 Jan 15;29(2):302-312. doi: 10.1016/j.bmcl.2018.11.030. Epub 2018 Nov 15. Bioorg Med Chem Lett. 2019. PMID: 30470490

8

Evaluation of amentoflavone metabolites on PARP-1 inhibition and the potentiation on anti-proliferative effects of carboplatin in A549 cells.

Wang B, Hu X, Wang R, Long H, Wang H. Wang B, et al. Among authors: wang h, wang r. Bioorg Med Chem Lett. 2022 Jan 15;56:128480. doi: 10.1016/j.bmcl.2021.128480. Epub 2021 Nov 26. Bioorg Med Chem Lett. 2022. PMID: 34843914

9

Discovery of Eucalyptin C, derived from the fruits of Eucalyptus globulus Labill., as a novel selective PI3Kγ inhibitor for immunosuppressive treatment.

Hu XL, Shen W, Wang R, Long H, Wang Q, Feng JH, Pham TA, Xiong F, Ye WC, Wang H. Hu XL, et al. Among authors: wang h, wang r, wang q. Chin J Nat Med. 2021 Nov;19(11):844-855. doi: 10.1016/S1875-5364(21)60111-5. Chin J Nat Med. 2021. PMID: 34844723

10

Proanthocyanidin A1 promotes the production of platelets to ameliorate chemotherapy-induced thrombocytopenia through activating JAK2/STAT3 pathway.

Wang R, Hu X, Wang J, Zhou L, Hong Y, Zhang Y, Xiong F, Zhang X, Ye WC, Wang H. Wang R, et al. Among authors: wang h, wang j. Phytomedicine. 2022 Jan;95:153880. doi: 10.1016/j.phymed.2021.153880. Epub 2021 Dec 5. Phytomedicine. 2022. PMID: 34906892

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