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Page 1
Epigenome-wide association studies identify novel DNA methylation sites associated with PTSD: a meta-analysis of 23 military and civilian cohorts.
Katrinli S, Wani AH, Maihofer AX, Ratanatharathorn A, Daskalakis NP, Montalvo-Ortiz J, Núñez-Ríos DL, Zannas AS, Zhao X, Aiello AE, Ashley-Koch AE, Avetyan D, Baker DG, Beckham JC, Boks MP, Brick LA, Bromet E, Champagne FA, Chen CY, Dalvie S, Dennis MF, Fatumo S, Fortier C, Galea S, Garrett ME, Geuze E, Grant G, Hauser MA, Hayes JP, Hemmings SMJ, Huber BR, Jajoo A, Jansen S, Kessler RC, Kimbrel NA, King AP, Kleinman JE, Koen N, Koenen KC, Kuan PF, Liberzon I, Linnstaedt SD, Lori A, Luft BJ, Luykx JJ, Marx CE, McLean SA, Mehta D, Milberg W, Miller MW, Mufford MS, Musanabaganwa C, Mutabaruka J, Mutesa L, Nemeroff CB, Nugent NR, Orcutt HK, Qin XJ, Rauch SAM, Ressler KJ, Risbrough VB, Rutembesa E, Rutten BPF, Seedat S, Stein DJ, Stein MB, Toikumo S, Ursano RJ, Uwineza A, Verfaellie MH, Vermetten E, Vinkers CH, Ware EB, Wildman DE, Wolf EJ, Young RM, Zhao Y, van den Heuvel LL; PGC-PTSD Epigenetics Workgroup; PsychENCODE PTSD Brainomics Project; Traumatic Stress Brain Research Group; Uddin M, Nievergelt CM, Smith AK, Logue MW. Katrinli S, et al. Among authors: ashley koch ae. Genome Med. 2024 Dec 18;16(1):147. doi: 10.1186/s13073-024-01417-1. Genome Med. 2024. PMID: 39696436 Free PMC article.
Performance of Polygenic Risk Scores for Primary Open-Angle Glaucoma in Populations of African Descent.
Chang-Wolf JM, Kinzy TG, Driessen SJ, Cruz LA, Iyengar SK, Peachey NS, Aung T, Khor CC, Williams SE, Ramsay M, Olawoye O, Ashaye A, Klaver CCW, Hauser MA, Thiadens AAHJ, Cooke Bailey JN, Bonnemaijer PWM; Genetics in Glaucoma Patients of African Descent (GIGA) Study GroupGenetics of Glaucoma in People of African Descent (GGLAD) Study GroupMillion Veteran Program (MVP). Chang-Wolf JM, et al. JAMA Ophthalmol. 2024 Nov 14:e244784. doi: 10.1001/jamaophthalmol.2024.4784. Online ahead of print. JAMA Ophthalmol. 2024. PMID: 39541127
Accelerated epigenetic aging and prospective morbidity and mortality among U.S. veterans.
Bourassa KJ, Anderson L, Woolson S, Dennis PA, Garrett ME, Hair L, Dennis M, Sugden K, Williams B, Houts R; VA Mid Atlantic MIRECC Workgroup; Calhoun PS, Naylor JC, Ashley-Koch AE, Beckham JC, Caspi A, Taylor GA, Hall KS, Moffitt TE, Kimbrel NA. Bourassa KJ, et al. Among authors: ashley koch ae. medRxiv [Preprint]. 2024 Oct 23:2024.10.23.24315691. doi: 10.1101/2024.10.23.24315691. medRxiv. 2024. PMID: 39502668 Free PMC article. Preprint.
Genomic structural equation modeling reveals latent phenotypes in the human cortex with distinct genetic architecture.
Morey RA, Zheng Y, Bayly H, Sun D, Garrett ME, Gasperi M, Maihofer AX, Baird CL, Grasby KL, Huggins AA, Haswell CC, Thompson PM, Medland S, Gustavson DE, Panizzon MS, Kremen WS, Nievergelt CM, Ashley-Koch AE, Logue MW. Morey RA, et al. Among authors: ashley koch ae. Transl Psychiatry. 2024 Oct 24;14(1):451. doi: 10.1038/s41398-024-03152-y. Transl Psychiatry. 2024. PMID: 39448598 Free PMC article.
Analyses of GWAS signal using GRIN identify additional genes contributing to suicidal behavior.
Sullivan KA, Lane M, Cashman M, Miller JI, Pavicic M, Walker AM, Cliff A, Romero J, Qin X, Mullins N, Docherty A, Coon H, Ruderfer DM; International Suicide Genetics Consortium; VA Million Veteran Program; MVP Suicide Exemplar Workgroup; Garvin MR, Pestian JP, Ashley-Koch AE, Beckham JC, McMahon B, Oslin DW, Kimbrel NA, Jacobson DA, Kainer D. Sullivan KA, et al. Among authors: ashley koch ae. Commun Biol. 2024 Oct 21;7(1):1360. doi: 10.1038/s42003-024-06943-7. Commun Biol. 2024. PMID: 39433874 Free PMC article.
Whole-genome sequencing in 333,100 individuals reveals rare non-coding single variant and aggregate associations with height.
Hawkes G, Beaumont RN, Li Z, Mandla R, Li X, Albert CM, Arnett DK, Ashley-Koch AE, Ashrani AA, Barnes KC, Boerwinkle E, Brody JA, Carson AP, Chami N, Chen YI, Chung MK, Curran JE, Darbar D, Ellinor PT, Fornage M, Gordeuk VR, Guo X, He J, Hwu CM, Kalyani RR, Kaplan R, Kardia SLR, Kooperberg C, Loos RJF, Lubitz SA, Minster RL, Naseri T, Viali S, Mitchell BD, Murabito JM, Palmer ND, Psaty BM, Redline S, Shoemaker MB, Silverman EK, Telen MJ, Weiss ST, Yanek LR, Zhou H; NHLBI Trans-Omics for Precision Medicine (TOPMed) Consortium; Liu CT, North KE, Justice AE, Locke JM, Owens N, Murray A, Patel K, Frayling TM, Wright CF, Wood AR, Lin X, Manning A, Weedon MN. Hawkes G, et al. Among authors: ashley koch ae. Nat Commun. 2024 Oct 3;15(1):8549. doi: 10.1038/s41467-024-52579-w. Nat Commun. 2024. PMID: 39362880 Free PMC article.
Black Americans With Sickle Cell Disease (SCD) Demonstrate Accelerated Epigenetic Pace of Aging Compared to Black Americans Without SCD.
Garrett ME, Le B, Bourassa KJ, Dennis MF, Hatch D, Yang Q, Tanabe P, Shah N, Luyster FS, Oyedeji C, Strouse JJ, Cohen HJ, Kimbrel NA, Beckham JC, Knisely MR, Telen MJ, Ashley-Koch AE; VA Mid-Atlantic MIRECC Workgroup. Garrett ME, et al. Among authors: ashley koch ae. J Gerontol A Biol Sci Med Sci. 2024 Nov 1;79(11):glae230. doi: 10.1093/gerona/glae230. J Gerontol A Biol Sci Med Sci. 2024. PMID: 39297703
155 results