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Inhibition of nuclear export restores nuclear localization and residual tumor suppressor function of truncated SMARCB1/INI1 protein in a molecular subset of atypical teratoid/rhabdoid tumors.
Pathak R, Zin F, Thomas C, Bens S, Gayden T, Karamchandani J, Dudley RW, Nemes K, Johann PD, Oyen F, Kordes U, Jabado N, Siebert R, Paulus W, Kool M, Frühwald MC, Albrecht S, Kalpana GV, Hasselblatt M. Pathak R, et al. Among authors: kalpana gv. Acta Neuropathol. 2021 Aug;142(2):361-374. doi: 10.1007/s00401-021-02328-w. Epub 2021 May 18. Acta Neuropathol. 2021. PMID: 34003336 Free PMC article.
INI1/SMARCB1 Rpt1 domain mimics TAR RNA in binding to integrase to facilitate HIV-1 replication.
Dixit U, Bhutoria S, Wu X, Qiu L, Spira M, Mathew S, Harris R, Adams LJ, Cahill S, Pathak R, Rajesh Kumar P, Nguyen M, Acharya SA, Brenowitz M, Almo SC, Zou X, Steven AC, Cowburn D, Girvin M, Kalpana GV. Dixit U, et al. Among authors: kalpana gv. Nat Commun. 2021 May 12;12(1):2743. doi: 10.1038/s41467-021-22733-9. Nat Commun. 2021. PMID: 33980829 Free PMC article.
58 results