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The ATP-hydrolyzing ectoenzyme E-NTPD8 attenuates colitis through modulation of P2X4 receptor-dependent metabolism in myeloid cells.
Tani H, Li B, Kusu T, Okumura R, Nishimura J, Okuzaki D, Motooka D, Arakawa S, Mori A, Yoshihara T, Ogino T, Tsai SH, Furuta Y, Muneta M, Nakamura S, Fukusaki E, Yamamoto K, Yagita H, Kayama H, Takeda K. Tani H, et al. Among authors: nakamura s. Proc Natl Acad Sci U S A. 2021 Sep 28;118(39):e2100594118. doi: 10.1073/pnas.2100594118. Proc Natl Acad Sci U S A. 2021. PMID: 34548395 Free PMC article.
Heme ameliorates dextran sodium sulfate-induced colitis through providing intestinal macrophages with noninflammatory profiles.
Kayama H, Kohyama M, Okuzaki D, Motooka D, Barman S, Okumura R, Muneta M, Hoshino K, Sasaki I, Ise W, Matsuno H, Nishimura J, Kurosaki T, Nakamura S, Arase H, Kaisho T, Takeda K. Kayama H, et al. Among authors: nakamura s. Proc Natl Acad Sci U S A. 2018 Aug 14;115(33):8418-8423. doi: 10.1073/pnas.1808426115. Epub 2018 Jul 30. Proc Natl Acad Sci U S A. 2018. PMID: 30061415 Free PMC article.
High-fat diet promotes prostate cancer growth through histamine signaling.
Matsushita M, Fujita K, Hatano K, Hayashi T, Kayama H, Motooka D, Hase H, Yamamoto A, Uemura T, Yamamichi G, Tomiyama E, Koh Y, Kato T, Kawashima A, Uemura M, Nojima S, Imamura R, Mubeen A, Netto GJ, Tsujikawa K, Nakamura S, Takeda K, Morii E, Nonomura N. Matsushita M, et al. Among authors: nakamura s. Int J Cancer. 2022 Aug 15;151(4):623-636. doi: 10.1002/ijc.34028. Epub 2022 Apr 26. Int J Cancer. 2022. PMID: 35403732
Lysophosphatidylserines derived from microbiota in Crohn's disease elicit pathological Th1 response.
Otake-Kasamoto Y, Kayama H, Kishikawa T, Shinzaki S, Tashiro T, Amano T, Tani M, Yoshihara T, Li B, Tani H, Liu L, Hayashi A, Okuzaki D, Motooka D, Nakamura S, Okada Y, Iijima H, Takeda K, Takehara T. Otake-Kasamoto Y, et al. Among authors: nakamura s. J Exp Med. 2022 Jul 4;219(7):e20211291. doi: 10.1084/jem.20211291. Epub 2022 May 24. J Exp Med. 2022. PMID: 35608941 Free PMC article.
Sialylation shapes mucus architecture inhibiting bacterial invasion in the colon.
Taniguchi M, Okumura R, Matsuzaki T, Nakatani A, Sakaki K, Okamoto S, Ishibashi A, Tani H, Horikiri M, Kobayashi N, Yoshikawa HY, Motooka D, Okuzaki D, Nakamura S, Kida T, Kameyama A, Takeda K. Taniguchi M, et al. Among authors: nakamura s. Mucosal Immunol. 2023 Oct;16(5):624-641. doi: 10.1016/j.mucimm.2023.06.004. Epub 2023 Jul 13. Mucosal Immunol. 2023. PMID: 37385587 Free article.
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