Villar JAFP - Search Results

1

Evaluating the Immunoprotective and Diagnostic Potential of Schistosoma mansoni Epitopes from Sm050890 and Sm141290 Proteins Identified Through Reverse Vaccinology.

de Oliveira FM, Lopes GFM, Ribeiro RIMA, Villar JAFP, Fonseca CT, Lopes DO. de Oliveira FM, et al. Among authors: villar jafp. Acta Parasitol. 2025 Jan 7;70(1):14. doi: 10.1007/s11686-024-00981-1. Acta Parasitol. 2025. PMID: 39775981

2

Evaluation of Anti-Inflammatory Activity of the New Cardiotonic Steroid γ-Benzylidene Digoxin 8 (BD-8) in Mice.

Ferreira DA, Medeiros ABA, Soares MM, Lima ÉA, Oliveira GCSL, Leite MBDS, Machado MV, Villar JAFP, Barbosa LA, Scavone C, Moura MT, Rodrigues-Mascarenhas S. Ferreira DA, et al. Among authors: villar jafp. Cells. 2024 Sep 18;13(18):1568. doi: 10.3390/cells13181568. Cells. 2024. PMID: 39329752 Free PMC article.

3

Simplified Method for Kinetic and Thermodynamic Screening of Cardiotonic Steroids through the K⁺-Dependent Phosphatase Activity of Na⁺/K⁺-ATPase with Chromogenic pNPP Substrate.

Azalim-Neto P, Noël F, Silva SC, Villar JAFP, Barbosa L, O'Doherty GA, Quintas LEM. Azalim-Neto P, et al. Among authors: villar jafp. Mol Pharmacol. 2024 Oct 17;106(5):225-239. doi: 10.1124/molpharm.124.000934. Mol Pharmacol. 2024. PMID: 39187390

4

Digoxin Derivatives Sensitize a Saccharomyces cerevisiae Mutant Strain to Fluconazole by Inhibiting Pdr5p.

de Moraes DC, Tessis AC, Rollin-Pinheiro R, Princival JL, Villar JAFP, Barbosa LA, Barreto-Bergter E, Ferreira-Pereira A. de Moraes DC, et al. Among authors: villar jafp. J Fungi (Basel). 2022 Jul 25;8(8):769. doi: 10.3390/jof8080769. J Fungi (Basel). 2022. PMID: 35893137 Free PMC article.

5

Evaluation of Cardiotonic Steroid Modulation of Cellular Cholesterol and Phospholipid.

Silva LND, Garcia IJP, Valadares JMM, Pessoa MTC, Toledo MM, Machado MV, Busch MS, Rocha I, Villar JAFP, Atella GC, Santos HL, Cortes VF, Barbosa LA. Silva LND, et al. Among authors: villar jafp. J Membr Biol. 2021 Dec;254(5-6):499-512. doi: 10.1007/s00232-021-00203-z. Epub 2021 Oct 29. J Membr Biol. 2021. PMID: 34716469

6

Alkaloid and phenolic compounds of Xylopia aromatica inhibits tumor growth by down-regulating matrix metalloproteinase-2 (MMP-2) expression.

Gomes INF, Silva AG, Frazao Lima GF, Longatti TR, Do Carmo LF, Villar JAFP, Araujo AADC, Tome RG, Santos HBD, Azambuja Ribeiro RIM. Gomes INF, et al. Among authors: villar jafp. Pak J Pharm Sci. 2021 Mar;34(2):599-606. Pak J Pharm Sci. 2021. PMID: 34275835

7

Implications of Synthetic Modifications of the Cardiotonic Steroid Lactone Ring on Cytotoxicity.

de Oliveira GC, Rocha SC, da Silva Lopes MA, Paixão N, Alves SLG, Pessoa MTC, Noël F, Quintas LEM, Barbosa LA, Villar JAFP, Cortes VF. de Oliveira GC, et al. Among authors: villar jafp. J Membr Biol. 2021 Dec;254(5-6):487-497. doi: 10.1007/s00232-021-00186-x. Epub 2021 Jun 14. J Membr Biol. 2021. PMID: 34128090

8

The γ-Benzylidene Digoxin Derivative BD-15 Increases the α3-Na, K-ATPase Activity in Rat Hippocampus and Prefrontal Cortex and no Change on Heart.

Parreira GM, Faria JA, Marques SMS, Garcia IJP, Silva IF, De Carvalho LED, Villar JAFP, Machado MV, de Castro Lima M, Barbosa LA, Cortes VF, de Lima Santos H. Parreira GM, et al. Among authors: villar jafp. J Membr Biol. 2021 Apr;254(2):189-199. doi: 10.1007/s00232-021-00173-2. Epub 2021 Feb 18. J Membr Biol. 2021. PMID: 33598793

9

21-Benzylidene digoxin decreases proliferation by inhibiting the EGFR/ERK signaling pathway and induces apoptosis in HeLa cells.

Pessôa MTC, Valadares JMM, Rocha SC, Silva SC, McDermott JP, Sánchez G, Varotti FP, Scavone C, Ribeiro RIMA, Villar JAFP, Blanco G, Barbosa LA. Pessôa MTC, et al. Among authors: villar jafp. Steroids. 2020 Mar;155:108551. doi: 10.1016/j.steroids.2019.108551. Epub 2019 Dec 6. Steroids. 2020. PMID: 31812624 Free PMC article.

10

Pharmacologic potential of new nitro-compounds as antimicrobial agents against nosocomial pathogens: design, synthesis, and in vitro effectiveness.

Andrade JT, Alves SLG, Lima WG, Sousa CDF, Carmo LF, De Sá NP, Morais FB, Johann S, Villar JAFP, Ferreira JMS. Andrade JT, et al. Among authors: villar jafp. Folia Microbiol (Praha). 2020 Apr;65(2):393-405. doi: 10.1007/s12223-019-00747-7. Epub 2019 Aug 10. Folia Microbiol (Praha). 2020. PMID: 31401762

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