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CRISPR targeting of FOXL2 c.402C>G mutation reduces malignant phenotype in granulosa tumor cells and identifies anti-tumoral compounds.
Amarilla-Quintana S, Navarro P, Hernández I, Ramos A, Montero-Calle A, Cabezas-Sainz P, Barrero MJ, Megías D, Vilaplana-Martí B, Epifano C, Gómez-Dominguez D, Monzón S, Cuesta I, Sánchez L, Barderas R, García-Donas J, Martín A, Pérez de Castro I. Amarilla-Quintana S, et al. Among authors: megias d. Mol Oncol. 2025 Jan 8. doi: 10.1002/1878-0261.13799. Online ahead of print. Mol Oncol. 2025. PMID: 39776254 Free article.
Perioperative chemoimmunotherapy induces strong immune responses and long-term survival in patients with HLA class I-deficient non-small cell lung cancer.
Molina-Alejandre M, Perea F, Calvo V, Martinez-Toledo C, Nadal E, Sierra-Rodero B, Casarrubios M, Casal-Rubio J, Martinez-Martí A, Insa A, Massuti B, Viteri S, Barneto Aranda I, Rodriguez-Abreu D, de Castro J, Martínez JM, Cobo M, Wistuba II, Parra ER, Martín-López J, Megías D, Muñoz-Viana R, Garrido F, Aptsiauri N, Ruiz-Cabello F, Provencio M, Cruz-Bermúdez A. Molina-Alejandre M, et al. Among authors: megias d. J Immunother Cancer. 2024 Oct 20;12(10):e009762. doi: 10.1136/jitc-2024-009762. J Immunother Cancer. 2024. PMID: 39428126 Free PMC article.
Dasatinib interferes with HIV-1 proviral integration and the inflammatory potential of monocyte-derived macrophages from people with HIV.
Rodríguez-Mora S, Sánchez-Menéndez C, Bautista-Carrascosa G, Mateos E, Moreno-Serna L, Megías D, Cantón J, García-Gutiérrez V, Murciano-Antón MA, Cervero M, Spivak A, Planelles V, Coiras M. Rodríguez-Mora S, et al. Among authors: megias d. Biochem Pharmacol. 2024 Nov;229:116512. doi: 10.1016/j.bcp.2024.116512. Epub 2024 Sep 1. Biochem Pharmacol. 2024. PMID: 39222713 Free article.
NKG2C/KLRC2 tumor cell expression enhances immunotherapeutic efficacy against glioblastoma.
de Dios O, Ramírez-González MA, Gómez-Soria I, Segura-Collar B, Manosalva J, Megías D, De Andrea CE, Fernández-Rubio L, Hernández-Laín A, Sepúlveda-Sánchez JM, Rodriguez-Ruiz ME, Pérez-Núñez Á, Wainwright DA, Gargini R, Sánchez-Gómez P. de Dios O, et al. Among authors: megias d. J Immunother Cancer. 2024 Aug 30;12(8):e009210. doi: 10.1136/jitc-2024-009210. J Immunother Cancer. 2024. PMID: 39214651 Free PMC article.
Effect of Cyclin-Dependent Kinase 4/6 Inhibitors on Circulating Cells in Patients with Metastatic Breast Cancer.
Lobo-Martins S, Corredeira P, Cavaco A, Rodrigues C, Piairo P, Lopes C, Fraga J, Silva M, Alves P, Wachholz Szeneszi L, Barradas A, Castro Duran C, Antunes M, Nogueira-Costa G, Sousa R, Pinto C, Ribeiro L, Abreu C, Torres S, Quintela A, Mata G, Megías D, Ribot J, Serre K, Casimiro S, Silva-Santos B, Diéguez L, Costa L. Lobo-Martins S, et al. Among authors: megias d. Cells. 2024 Aug 21;13(16):1391. doi: 10.3390/cells13161391. Cells. 2024. PMID: 39195280 Free PMC article.
A Randomised Phase II Trial of Hippocampal Sparing Versus Conventional Whole Brain Radiotherapy After Surgical Resection or Radiosurgery in Favourable Prognosis Patients With 1-10 Brain Metastases.
Whitfield GA, Bulbeck H, Clifton-Hadley L, Edwards D, Jefferies S, Jenkinson MD, Griffin M, Handley J, Megias D, Sanghera P, Shaffer R, Short S, Wilson W. Whitfield GA, et al. Among authors: megias d. Clin Oncol (R Coll Radiol). 2024 Nov;36(11):681-689. doi: 10.1016/j.clon.2024.07.001. Epub 2024 Jul 4. Clin Oncol (R Coll Radiol). 2024. PMID: 39030085 Free article. Clinical Trial.
123 results