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The microbiota-derived bile acid taurodeoxycholic acid improves hepatic cholesterol levels in mice with cancer cachexia.
Thibaut MM, Roumain M, Piron E, Gillard J, Loriot A, Neyrinck AM, Rodriguez J, Massart I, Thissen JP, Huot JR, Pin F, Bonetto A, Delzenne NM, Muccioli GG, Bindels LB. Thibaut MM, et al. Among authors: pin f. Gut Microbes. 2025 Dec;17(1):2449586. doi: 10.1080/19490976.2025.2449586. Epub 2025 Jan 8. Gut Microbes. 2025. PMID: 39780051 Free PMC article.
PDK4 drives metabolic alterations and muscle atrophy in cancer cachexia.
Pin F, Novinger LJ, Huot JR, Harris RA, Couch ME, O'Connell TM, Bonetto A. Pin F, et al. FASEB J. 2019 Jun;33(6):7778-7790. doi: 10.1096/fj.201802799R. Epub 2019 Mar 20. FASEB J. 2019. PMID: 30894018 Free PMC article.
Our data support, for the first time, a direct role for PDK4 in promoting cancer-associated muscle metabolic alterations and skeletal muscle atrophy.-Pin, F., Novinger, L. J., Huot, J. R., Harris, R. A., Couch, M. E., O'Connell, T. M., Bonetto, A. ...
Our data support, for the first time, a direct role for PDK4 in promoting cancer-associated muscle metabolic alterations and skeletal muscle …
Role of myokines and osteokines in cancer cachexia.
Pin F, Bonewald LF, Bonetto A. Pin F, et al. Exp Biol Med (Maywood). 2021 Oct;246(19):2118-2127. doi: 10.1177/15353702211009213. Epub 2021 Apr 25. Exp Biol Med (Maywood). 2021. PMID: 33899538 Free PMC article. Review.
73 results