Controlling Disassembly of Paramagnetic Prodrug and Photosensitizer Nanoassemblies for On-Demand Orthotopic Glioma Theranostics.
An R, Liu L, Wei S, Huang Z, Qiu L, Lin J, Liu H, Ye D.
An R, et al.
ACS Nano. 2022 Dec 27;16(12):20607-20621. doi: 10.1021/acsnano.2c07491. Epub 2022 Dec 12.
ACS Nano. 2022.
PMID: 36508254
Co-NP-RGD(1/1) is formed via molecular coassembly of two paramagnetic and fluorogenic small-molecule probes CPT-RGD and PPa-RGD at an optimized molar ratio of 1/1, which shows a high longitudinal relaxivity (r(1) = 17.0 0.6 mM(-1) s(-1), 0.5 T) but weak FL emissions …
Co-NP-RGD(1/1) is formed via molecular coassembly of two paramagnetic and fluorogenic small-molecule probes CPT-RGD and PPa-RGD at an …