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Host cell lectins ASGR1 and DC-SIGN jointly with TMEM106B confer ACE2 independence and imdevimab resistance to SARS-CoV-2 pseudovirus with spike mutation E484D.
Arora P, Zhang L, Nehlmeier I, Kempf A, Graichen L, Kreitz E, Sidarovich A, Rocha C, Gärtner S, Winkler M, Schulz S, Jäck H-M, Hoffmann M, Pöhlmann S. Arora P, et al. Among authors: hoffmann m. J Virol. 2025 Jan 10:e0123024. doi: 10.1128/jvi.01230-24. Online ahead of print. J Virol. 2025. PMID: 39791910
Quantifying the potential contribution of drugs to the occurrence of acute kidney injury in patients with chronic kidney disease.
Laville SM, Vendar J, Massy ZA, Gras-Champel V, Moragny J, Frimat L, Laville M, Jacquelinet C, Pecoits-Filho R, Alencar De Pinho N, Hamroun A, Liabeuf S; Chronic Kidney Disease-Renal Epidemiology and Information Network (CKD-REIN) Study Group. Laville SM, et al. Clin Kidney J. 2024 Nov 18;18(1):sfae357. doi: 10.1093/ckj/sfae357. eCollection 2025 Jan. Clin Kidney J. 2024. PMID: 39781474 Free PMC article.
The utility of the Living Planet Index as a policy tool and for measuring nature recovery.
McRae L, Cornford R, Marconi V, Puleston H, Ledger SEH, Deinet S, Oppenheimer P, Hoffmann M, Freeman R. McRae L, et al. Among authors: hoffmann m. Philos Trans R Soc Lond B Biol Sci. 2025 Jan 9;380(1917):20230207. doi: 10.1098/rstb.2023.0207. Epub 2025 Jan 9. Philos Trans R Soc Lond B Biol Sci. 2025. PMID: 39780599 Free PMC article.
Measuring trends in extinction risk: a review of two decades of development and application of the Red List Index.
Butchart SHM, Akçakaya HR, Berryman AJ, Brooks TM, Burfield IJ, Chanson J, Dias MP, Donaldson JS, Hermes C, Hilton-Taylor C, Hoffmann M, Luedtke JA, Martin R, McDougall A, Neam K, Polidoro B, Raimondo D, Rodrigues ASL, Rondinini C, Rutherford C, Scott T, Simkins AT, Stuart SN, Vine J. Butchart SHM, et al. Among authors: hoffmann m. Philos Trans R Soc Lond B Biol Sci. 2025 Jan 9;380(1917):20230206. doi: 10.1098/rstb.2023.0206. Epub 2025 Jan 9. Philos Trans R Soc Lond B Biol Sci. 2025. PMID: 39780598 Free PMC article. Review.
One-quarter of freshwater fauna threatened with extinction.
Sayer CA, Fernando E, Jimenez RR, Macfarlane NBW, Rapacciuolo G, Böhm M, Brooks TM, Contreras-MacBeath T, Cox NA, Harrison I, Hoffmann M, Jenkins R, Smith KG, Vié JC, Abbott JC, Allen DJ, Allen GR, Barrios V, Boudot JP, Carrizo SF, Charvet P, Clausnitzer V, Congiu L, Crandall KA, Cumberlidge N, Cuttelod A, Dalton J, Daniels AG, De Grave S, De Knijf G, Dijkstra KB, Dow RA, Freyhof J, García N, Gessner J, Getahun A, Gibson C, Gollock MJ, Grant MI, Groom AER, Hammer MP, Hammerson GA, Hilton-Taylor C, Hodgkinson L, Holland RA, Jabado RW, Juffe Bignoli D, Kalkman VJ, Karimov BK, Kipping J, Kottelat M, Lalèyè PA, Larson HK, Lintermans M, Lozano F, Ludwig A, Lyons TJ, Máiz-Tomé L, Molur S, Ng HH, Numa C, Palmer-Newton AF, Pike C, Pippard HE, Polaz CNM, Pollock CM, Raghavan R, Rand PS, Ravelomanana T, Reis RE, Rigby CL, Scott JA, Skelton PH, Sloat MR, Snoeks J, Stiassny MLJ, Tan HH, Taniguchi Y, Thorstad EB, Tognelli MF, Torres AG, Torres Y, Tweddle D, Watanabe K, Westrip JRS, Wright EGE, Zhang E, Darwall WRT. Sayer CA, et al. Among authors: hoffmann m. Nature. 2025 Jan 8. doi: 10.1038/s41586-024-08375-z. Online ahead of print. Nature. 2025. PMID: 39779863
Immune Response to SARS-CoV-2 XBB.1.5 and JN.1 Variants Following XBB.1.5 Booster Vaccination in Liver Transplant Recipients.
von der Schulenburg P, Behrens GMN, Hoffmann M, Linke A, Nehlmeier I, Kempf AM, Stankov M, Lütgehetmann M, Jahnke-Triankowski J, Addo MM, Fischer L, Lohse AW, Pöhlmann S, Schulze Zur Wiesch J, Sterneck M. von der Schulenburg P, et al. Among authors: hoffmann m. Viruses. 2024 Dec 19;16(12):1942. doi: 10.3390/v16121942. Viruses. 2024. PMID: 39772248 Free PMC article.
Selectively expressed RNA molecules as a versatile tool for functionalized cell targeting.
Rastfeld F, Hoffmann M, Krüger S, Bohn P, Gribling-Burrer AS, Wagner L, Hersch N, Stegmayr C, Lövenich L, Gerlach S, Köninger D, Hoffmann C, Walter HL, Wiedermann D, Manoharan H, Fink GR, Merkel R, Bohlen H, Smyth RP, Rueger MA, Hoffmann B. Rastfeld F, et al. Among authors: hoffmann m. Nat Commun. 2025 Jan 6;16(1):420. doi: 10.1038/s41467-024-55547-6. Nat Commun. 2025. PMID: 39762287 Free PMC article.
Affinity maturation endows potent activity onto class 6 SARS-CoV-2 broadly neutralizing antibodies.
Mazigi O, Langley DB, Henry JY, Burnett DL, Sobti M, Walker GJ, Rouet R, Balachandran H, Lenthall H, Jackson J, Ubiparipovic S, Schofield P, Brown SHJ, Schulz SR, Hoffmann M, Pöhlmann S, Post J, Martinello M, Ahlenstiel G, Kelleher A, Rawlinson WD, Turville SG, Bull RA, Stewart AG, Jäck HM, Goodnow CC, Christ D. Mazigi O, et al. Among authors: hoffmann m. Proc Natl Acad Sci U S A. 2025 Jan 7;122(1):e2417544121. doi: 10.1073/pnas.2417544121. Epub 2025 Jan 2. Proc Natl Acad Sci U S A. 2025. PMID: 39746041 Free article.
3,684 results