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Page 1
Transmembrane protein 97 is a potential synaptic amyloid beta receptor in human Alzheimer's disease.
Colom-Cadena M, Toombs J, Simzer E, Holt K, McGeachan R, Tulloch J, Jackson RJ, Catterson JH, Spires-Jones MP, Rose J, Waybright L, Caggiano AO, King D, Gobbo F, Davies C, Hooley M, Dunnett S, Tempelaar R, Meftah S, Tzioras M, Hamby ME, Izzo NJ, Catalano SM, Durrant CS, Smith C, Dando O, Spires-Jones TL. Colom-Cadena M, et al. Among authors: simzer e. Acta Neuropathol. 2024 Feb 6;147(1):32. doi: 10.1007/s00401-023-02679-6. Acta Neuropathol. 2024. PMID: 38319380 Free PMC article.
p-tau Ser356 is associated with Alzheimer's disease pathology and is lowered in brain slice cultures using the NUAK inhibitor WZ4003.
Taylor LW, Simzer EM, Pimblett C, Lacey-Solymar OTT, McGeachan RI, Meftah S, Rose JL, Spires-Jones MP, Holt K, Catterson JH, Koch H, Liaquat I, Clarke JH, Skidmore J, Smith C, Booker SA, Brennan PM, Spires-Jones TL, Durrant CS. Taylor LW, et al. Among authors: simzer em. Acta Neuropathol. 2024 Jan 4;147(1):7. doi: 10.1007/s00401-023-02667-w. Acta Neuropathol. 2024. PMID: 38175261 Free PMC article.
Synaptic oligomeric tau in Alzheimer's disease - A potential culprit in the spread of tau pathology through the brain.
Colom-Cadena M, Davies C, Sirisi S, Lee JE, Simzer EM, Tzioras M, Querol-Vilaseca M, Sánchez-Aced É, Chang YY, Holt K, McGeachan RI, Rose J, Tulloch J, Wilkins L, Smith C, Andrian T, Belbin O, Pujals S, Horrocks MH, Lleó A, Spires-Jones TL. Colom-Cadena M, et al. Among authors: simzer em. Neuron. 2023 Jul 19;111(14):2170-2183.e6. doi: 10.1016/j.neuron.2023.04.020. Epub 2023 May 15. Neuron. 2023. PMID: 37192625 Free article.
Reflections on the Brain Conference 2023.
Simzer E. Simzer E. Brain Commun. 2023 May 3;5(3):fcad102. doi: 10.1093/braincomms/fcad102. eCollection 2023. Brain Commun. 2023. PMID: 37151222 Free PMC article.