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Data-driven CSF biomarker profiling: imaging and clinical outcomes in a cohort at risk of Alzheimer's disease.
Argiris G, Akinci M, Peña-Gómez C, Palpatzis E, Garcia-Prat M, Shekari M, Blennow K, Zetterberg H, Kollmorgen G, Quijano-Rubio C, Ashton NJ, Karikari TK, Brinkmalm-Westman A, Lantero-Rodriguez J, Fauria K, Sánchez-Benavides G, Grau-Rivera O, Suárez-Calvet M, Arenaza-Urquijo EM, Study FTA. Argiris G, et al. Among authors: kollmorgen g. Alzheimers Res Ther. 2024 Dec 23;16(1):274. doi: 10.1186/s13195-024-01629-y. Alzheimers Res Ther. 2024. PMID: 39716329 Free PMC article.
Amyloid-β positivity is less prevalent in cognitively unimpaired KLOTHO KL-VS heterozygotes.
Cook N, Driscoll I, Gaitán JM, Glittenberg M, Betthauser TJ, Carlsson CM, Johnson SC, Asthana S, Zetterberg H, Blennow K, Kollmorgen G, Quijano-Rubio C, Dubal DB, Okonkwo OC. Cook N, et al. Among authors: kollmorgen g. J Alzheimers Dis. 2024 Nov;102(2):480-490. doi: 10.1177/13872877241289785. Epub 2024 Nov 11. J Alzheimers Dis. 2024. PMID: 39529379
Pharmacodynamic effects of semorinemab on plasma and CSF biomarkers of Alzheimer's disease pathophysiology.
Schauer SP, Toth B, Lee J, Honigberg LA, Ramakrishnan V, Jiang J, Kollmorgen G, Bayfield A, Wild N, Hoffman J, Ceniceros R, Dolton M, Bohórquez SMS, Hoogenraad CC, Wildsmith KR, Teng E, Monteiro C, Anania V, Yeh FL. Schauer SP, et al. Among authors: kollmorgen g. Alzheimers Dement. 2024 Dec;20(12):8855-8866. doi: 10.1002/alz.14346. Epub 2024 Nov 8. Alzheimers Dement. 2024. PMID: 39513754 Free PMC article. Clinical Trial.
Misfolded alpha synuclein co-occurrence with Alzheimer's disease proteinopathy.
Jonaitis EM, MacLeod K, Lamoureux J, Jeffers B, Studer RL, Middleton J, Wilson RE, Chin NA, Okonkwo OC, Bendlin BB, Asthana S, Carlsson CM, Gallagher CL, Hermann B, McEvoy S, Kollmorgen G, Zetterberg H, Concha-Marambio L, Johnson SC, Lebovitz RM, Langhough RE. Jonaitis EM, et al. Among authors: kollmorgen g. medRxiv [Preprint]. 2024 Oct 13:2024.10.11.24315349. doi: 10.1101/2024.10.11.24315349. medRxiv. 2024. PMID: 39417113 Free PMC article. Preprint.
Sex/gender effects of glial reactivity on preclinical Alzheimer's disease pathology.
Vila-Castelar C, Akinci M, Palpatzis E, Aguilar-Dominguez P, Operto G, Kollmorgen G, Quijano-Rubio C, Blennow K, Zetterberg H, Falcon C, Fauria K, Gispert JD, Grau-Rivera O, Suárez-Calvet M, Arenaza-Urquijo EM; ALFA study. Vila-Castelar C, et al. Among authors: kollmorgen g. Mol Psychiatry. 2024 Oct 9. doi: 10.1038/s41380-024-02753-9. Online ahead of print. Mol Psychiatry. 2024. PMID: 39384963
CSF complement proteins are elevated in prodromal to moderate Alzheimer's disease patients and are not altered by the anti-tau antibody semorinemab.
Sandoval C, Lee J, Toth B, Nagaraj R, Schauer SP, Hoffman J, Calderon E, Kollmorgen G, Sanabria Bohórquez SM, Monteiro C, Teng E, Hanson JE, Yeh FL, Gutierrez J, Biever A. Sandoval C, et al. Among authors: kollmorgen g. Alzheimers Dement. 2024 Nov;20(11):7940-7953. doi: 10.1002/alz.14271. Epub 2024 Oct 6. Alzheimers Dement. 2024. PMID: 39369294 Free PMC article.
CSF glial biomarkers are associated with cognition in individuals at risk of Alzheimer's disease.
Warmenhoven N, Sánchez-Benavides G, González-Escalante A, Milà-Alomà M, Shekari M, López-Martos D, Ortiz-Romero P, Kollmorgen G, Quijano-Rubio C, Minguillón C, Gispert JD, Vilor-Tejedor N, Arenaza-Urquijo E, Palpatzis E, Ashton NJ, Zetterberg H, Blennow K, Suárez-Calvet M, Grau-Rivera O; ALFA Study. Warmenhoven N, et al. Among authors: kollmorgen g. Alzheimers Dement. 2024 Sep;20(9):5819-5832. doi: 10.1002/alz.13862. Epub 2024 Jul 19. Alzheimers Dement. 2024. PMID: 39032119 Free PMC article.
KLOTHO KL-VS heterozygosity is associated with diminished age-related neuroinflammation, neurodegeneration, and synaptic dysfunction in older cognitively unimpaired adults.
Driscoll IF, Lose S, Ma Y, Bendlin BB, Gallagher C, Johnson SC, Asthana S, Hermann B, Sager MA, Blennow K, Zetterberg H, Carlsson C, Kollmorgen G, Quijano-Rubio C, Dubal D, Okonkwo OC. Driscoll IF, et al. Among authors: kollmorgen g. Alzheimers Dement. 2024 Aug;20(8):5347-5356. doi: 10.1002/alz.13912. Epub 2024 Jun 21. Alzheimers Dement. 2024. PMID: 39030746 Free PMC article.
Time-encoded ASL reveals lower cerebral blood flow in the early AD continuum.
Falcon C, Montesinos P, Václavů L, Kassinopoulos M, Minguillon C, Fauria K, Cascales-Lahoz D, Contador J, Fernández-Lebrero A, Navalpotro I, Puig-Pijoan A, Grau-Rivera O, Kollmorgen G, Quijano-Rubio C, Molinuevo JL, Zetterberg H, Blennow K, Suárez-Calvet M, Van Osch MJP, Sanchez-Gonzalez J, Gispert JD. Falcon C, et al. Among authors: kollmorgen g. Alzheimers Dement. 2024 Aug;20(8):5183-5197. doi: 10.1002/alz.14059. Epub 2024 Jul 3. Alzheimers Dement. 2024. PMID: 38958557 Free PMC article.
102 results