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SAFETY, PHARMACOKINETICS, AND CLINICAL EFFICACY OF ADS051, A NEUTROPHIL MODULATOR, IN ULCERATIVE COLITIS: RESULTS OF A RANDOMIZED PHASE 1B TRIAL.
Allegretti JR, Cheifetz AS, Dulai PS, Stevens AC, Chapas-Reed J, Chesnel L, Dixit B, Farquhar R, Ghahramani P, Miller BW, Murphy CK, Quintas M, Tanase R, Telia T, Woźniak-Stolarska B, Gupta R. Allegretti JR, et al. Among authors: chesnel l. Am J Gastroenterol. 2024 Dec 31. doi: 10.14309/ajg.0000000000003269. Online ahead of print. Am J Gastroenterol. 2024. PMID: 39787364
ADS024, a single-strain live biotherapeutic product of Bacillus velezensis alleviates dextran sulfate-mediated colitis in mice, protects human colonic epithelial cells against apoptosis, and maintains epithelial barrier function.
Irwin S, Chupina Estrada A, Nelson B, Bullock A, Limketkai B, Ho W, Acton S, Chesnel L, Koon HW. Irwin S, et al. Among authors: chesnel l. Front Microbiol. 2024 Jan 10;14:1284083. doi: 10.3389/fmicb.2023.1284083. eCollection 2023. Front Microbiol. 2024. PMID: 38268707 Free PMC article.
LPAR3: a shared target for neurodegenerative diseases?
Acton S, Chesnel L. Acton S, et al. Among authors: chesnel l. Neural Regen Res. 2024 Dec 7. doi: 10.4103/NRR.NRR-D-24-01024. Online ahead of print. Neural Regen Res. 2024. PMID: 39665827 Free article. No abstract available.
Characterization of Clostridioides difficile isolates recovered from two Phase 3 surotomycin treatment trials by restriction endonuclease analysis, PCR ribotyping and antimicrobial susceptibilities.
Cheknis A, Devaris D, Chesnel L, Dale SE, Nary J, Sambol SP, Citron DM, Goering RV, Johnson S. Cheknis A, et al. Among authors: chesnel l. J Antimicrob Chemother. 2020 Nov 1;75(11):3120-3125. doi: 10.1093/jac/dkaa297. J Antimicrob Chemother. 2020. PMID: 32747931
37 results