Murphy CK - Search Results

1

SAFETY, PHARMACOKINETICS, AND CLINICAL EFFICACY OF ADS051, A NEUTROPHIL MODULATOR, IN ULCERATIVE COLITIS: RESULTS OF A RANDOMIZED PHASE 1B TRIAL.

Allegretti JR, Cheifetz AS, Dulai PS, Stevens AC, Chapas-Reed J, Chesnel L, Dixit B, Farquhar R, Ghahramani P, Miller BW, Murphy CK, Quintas M, Tanase R, Telia T, Woźniak-Stolarska B, Gupta R. Allegretti JR, et al. Among authors: murphy ck. Am J Gastroenterol. 2024 Dec 31. doi: 10.14309/ajg.0000000000003269. Online ahead of print. Am J Gastroenterol. 2024. PMID: 39787364

2

Small-Molecule Neutrophil Modulator ADS051 is Safe and Well-Tolerated in a Phase 1 Single Ascending Dose Study.

Cheifetz AS, Allegretti JR, Quintas M, Dixit B, Farquhar R, Miller BW, Murphy CK, Hershberger E, Ghahramani P, Stevens AC. Cheifetz AS, et al. Among authors: murphy ck. Am J Gastroenterol. 2024 Nov 26. doi: 10.14309/ajg.0000000000003237. Online ahead of print. Am J Gastroenterol. 2024. PMID: 39588987

3

Novel, non-colonizing, single-strain live biotherapeutic product ADS024 protects against Clostridioides difficile infection challenge in vivo.

Murphy CK, O'Donnell MM, Hegarty JW, Schulz S, Hill C, Ross RP, Rea MC, Farquhar R, Chesnel L. Murphy CK, et al. World J Gastrointest Pathophysiol. 2023 Aug 24;14(4):71-85. doi: 10.4291/wjgp.v14.i4.71. World J Gastrointest Pathophysiol. 2023. PMID: 37727283 Free PMC article.

4

Development of ADS051, an oral, gut-restricted, small molecule neutrophil modulator for the treatment of neutrophil-mediated inflammatory diseases.

Murphy CK, Dixit B, Oleson FB, Dolle RE, Farquhar R, McCormick BA. Murphy CK, et al. FEBS Open Bio. 2023 Aug;13(8):1434-1446. doi: 10.1002/2211-5463.13668. Epub 2023 Jul 10. FEBS Open Bio. 2023. PMID: 37392453 Free PMC article.

5

A novel dual NLRP1 and NLRP3 inflammasome inhibitor for the treatment of inflammatory diseases.

Docherty CA, Fernando AJ, Rosli S, Lam M, Dolle RE, Navia MA, Farquhar R, La France D, Tate MD, Murphy CK, Rossi AG, Mansell A. Docherty CA, et al. Among authors: murphy ck. Clin Transl Immunology. 2023 Jun 22;12(6):e1455. doi: 10.1002/cti2.1455. eCollection 2023. Clin Transl Immunology. 2023. PMID: 37360982 Free PMC article.

6

Selective small molecule targeting β-catenin function discovered by in vivo chemical genetic screen.

Hao J, Ao A, Zhou L, Murphy CK, Frist AY, Keel JJ, Thorne CA, Kim K, Lee E, Hong CC. Hao J, et al. Among authors: murphy ck. Cell Rep. 2013 Sep 12;4(5):898-904. doi: 10.1016/j.celrep.2013.07.047. Epub 2013 Sep 5. Cell Rep. 2013. PMID: 24012757 Free PMC article.

7

Update on health reform: ENA's health care reform platform.

Murphy CK. Murphy CK. J Emerg Nurs. 2010 Sep;36(5):479-82. doi: 10.1016/j.jen.2010.06.018. Epub 2010 Aug 1. J Emerg Nurs. 2010. PMID: 20837222 No abstract available.

8

Perceptions of HIV/AIDS leaders about faith-based organisations' influence on HIV/AIDS stigma in South Africa.

Keikelame MJ, Murphy CK, Ringheim KE, Woldehanna S. Keikelame MJ, et al. Among authors: murphy ck. Afr J AIDS Res. 2010 Apr;9(1):63-70. doi: 10.2989/16085906.2010.484571. Afr J AIDS Res. 2010. PMID: 25860414

9

Rifalazil retains activity against rifampin-resistant mutants of Chlamydia pneumoniae.

Rothstein DM, Suchland RJ, Xia M, Murphy CK, Stamm WE. Rothstein DM, et al. Among authors: murphy ck. J Antibiot (Tokyo). 2008 Aug;61(8):489-95. doi: 10.1038/ja.2008.65. J Antibiot (Tokyo). 2008. PMID: 18997387

10

Rifalazil and derivative compounds show potent efficacy in a mouse model of H. pylori colonization.

Rothstein DM, Mullin S, Sirokman K, Söndergaard KL, Johnson S, Gwathmey JK, van Duzer J, Murphy CK. Rothstein DM, et al. Among authors: murphy ck. J Antibiot (Tokyo). 2008 Aug;61(8):485-8. doi: 10.1038/ja.2008.64. J Antibiot (Tokyo). 2008. PMID: 18997386

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