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Previous short-term disuse dictates muscle gene expression and physiological adaptations to subsequent resistance exercise.
Franchi MV, Candia J, Sarto F, Sirago G, Valli G, Paganini M, Hartnell L, Giacomello E, Toniolo L, Monti E, Nogara L, Moro T, Paoli A, Murgia M, Brocca L, Pellegrino MA, Grassi B, Bottinelli R, De Vito G, Ferrucci L, Narici MV. Franchi MV, et al. Among authors: nogara l. J Physiol. 2025 Jan 10. doi: 10.1113/JP287003. Online ahead of print. J Physiol. 2025. PMID: 39792484
Reduced ATP turnover during hibernation in relaxed skeletal muscle.
De Napoli C, Schmidt L, Montesel M, Cussonneau L, Sanniti S, Marcucci L, Germinario E, Kindberg J, Evans AL, Gauquelin-Koch G, Narici M, Bertile F, Lefai E, Krüger M, Nogara L, Blaauw B. De Napoli C, et al. Among authors: nogara l. Nat Commun. 2025 Jan 2;16(1):80. doi: 10.1038/s41467-024-55565-4. Nat Commun. 2025. PMID: 39747078 Free PMC article.
Mitochondrial calcium uptake declines during aging and is directly activated by oleuropein to boost energy metabolism and skeletal muscle performance.
Gherardi G, Weiser A, Bermont F, Migliavacca E, Brinon B, Jacot GE, Hermant A, Sturlese M, Nogara L, Vascon F, De Mario A, Mattarei A, Garratt E, Burton M, Lillycrop K, Godfrey KM, Cendron L, Barron D, Moro S, Blaauw B, Rizzuto R, Feige JN, Mammucari C, De Marchi U. Gherardi G, et al. Among authors: nogara l. Cell Metab. 2024 Nov 23:S1550-4131(24)00417-0. doi: 10.1016/j.cmet.2024.10.021. Online ahead of print. Cell Metab. 2024. PMID: 39603237 Free article.
Salbutamol repurposing ameliorates neuromuscular junction defects and muscle atrophy in Col6a1-/- mouse model of collagen VI-related myopathies.
Calabrò S, Nogara L, Jian Y, Valentin M, Bizzotto D, Braghetta P, Russo L, Gambarotto L, Blaauw B, Hashemolhosseini S, Bonaldo P, Cescon M. Calabrò S, et al. Among authors: nogara l. Clin Transl Med. 2024 Jul;14(7):e1688. doi: 10.1002/ctm2.1688. Clin Transl Med. 2024. PMID: 38984773 Free PMC article. No abstract available.
A Novel MAO-B/SSAO Inhibitor Improves Multiple Aspects of Dystrophic Phenotype in mdx Mice.
Gasparella F, Nogara L, Germinario E, Tibaudo L, Ciciliot S, Piccoli G, Venegas FC, Fontana F, Sales G, Sabbatini D, Foot J, Jarolimek W, Blaauw B, Canton M, Vitiello L. Gasparella F, et al. Among authors: nogara l. Antioxidants (Basel). 2024 May 21;13(6):622. doi: 10.3390/antiox13060622. Antioxidants (Basel). 2024. PMID: 38929061 Free PMC article.
SEPN1-related myopathy depends on the oxidoreductase ERO1A and is druggable with the chemical chaperone TUDCA.
Germani S, Van Ho AT, Cherubini A, Varone E, Chernorudskiy A, Renna GM, Fumagalli S, Gobbi M, Lucchetti J, Bolis M, Guarrera L, Craparotta I, Rastelli G, Piccoli G, de Napoli C, Nogara L, Poggio E, Brini M, Cattaneo A, Bachi A, Simmen T, Calì T, Quijano-Roy S, Boncompagni S, Blaauw B, Ferreiro A, Zito E. Germani S, et al. Among authors: nogara l. Cell Rep Med. 2024 Mar 19;5(3):101439. doi: 10.1016/j.xcrm.2024.101439. Epub 2024 Feb 22. Cell Rep Med. 2024. PMID: 38402623 Free PMC article.
KBTBD13 is an actin-binding protein that modulates muscle kinetics.
de Winter JM, Molenaar JP, Yuen M, van der Pijl R, Shen S, Conijn S, van de Locht M, Willigenburg M, Bogaards SJ, van Kleef ES, Lassche S, Persson M, Rassier DE, Sztal TE, Ruparelia AA, Oorschot V, Ramm G, Hall TE, Xiong Z, Johnson CN, Li F, Kiss B, Lozano-Vidal N, Boon RA, Marabita M, Nogara L, Blaauw B, Rodenburg RJ, Küsters B, Doorduin J, Beggs AH, Granzier H, Campbell K, Ma W, Irving T, Malfatti E, Romero NB, Bryson-Richardson RJ, van Engelen BG, Voermans NC, Ottenheijm CA. de Winter JM, et al. Among authors: nogara l. J Clin Invest. 2024 Feb 1;134(3):e179111. doi: 10.1172/JCI179111. J Clin Invest. 2024. PMID: 38299595 Free PMC article. No abstract available.
36 results