Lombardi O - Search Results

1

Conserved patterns of transcriptional dysregulation, heterogeneity, and cell states in clear cell kidney cancer.

Lombardi O, Li R, Jabbar F, Evans H, Halim S, Lima JDCC, Browning L, Byrne HM, Choudhry H, Ratcliffe PJ, Mole DR. Lombardi O, et al. Cell Rep. 2025 Jan 8;44(1):115169. doi: 10.1016/j.celrep.2024.115169. Online ahead of print. Cell Rep. 2025. PMID: 39792555 Free article.

2

Pan-cancer analysis of tissue and single-cell HIF-pathway activation using a conserved gene signature.

Lombardi O, Li R, Halim S, Choudhry H, Ratcliffe PJ, Mole DR. Lombardi O, et al. Cell Rep. 2022 Nov 15;41(7):111652. doi: 10.1016/j.celrep.2022.111652. Cell Rep. 2022. PMID: 36384128 Free PMC article.

3

Co-incidence of RCC-susceptibility polymorphisms with HIF cis-acting sequences supports a pathway tuning model of cancer.

Schmid V, Lafleur VN, Lombardi O, Li R, Salama R, Colli L, Choudhry H, Chanock S, Ratcliffe PJ, Mole DR. Schmid V, et al. Among authors: lombardi o. Sci Rep. 2019 Dec 10;9(1):18768. doi: 10.1038/s41598-019-55098-7. Sci Rep. 2019. PMID: 31822727 Free PMC article.

4

Oncogenic Cell Tagging and Single-Cell Transcriptomics Reveal Cell Type-Specific and Time-Resolved Responses to Vhl Inactivation in the Kidney.

Kurlekar S, Lima JDCC, Li R, Lombardi O, Masson N, Barros AB, Pontecorvi V, Mole DR, Pugh CW, Adam J, Ratcliffe PJ. Kurlekar S, et al. Among authors: lombardi o. Cancer Res. 2024 Jun 4;84(11):1799-1816. doi: 10.1158/0008-5472.CAN-23-3248. Cancer Res. 2024. PMID: 38502859 Free PMC article.

5

Hypoxia drives glucose transporter 3 expression through hypoxia-inducible transcription factor (HIF)-mediated induction of the long noncoding RNA NICI.

Lauer V, Grampp S, Platt J, Lafleur V, Lombardi O, Choudhry H, Kranz F, Hartmann A, Wullich B, Yamamoto A, Coleman ML, Ratcliffe PJ, Mole DR, Schödel J. Lauer V, et al. Among authors: lombardi o. J Biol Chem. 2020 Mar 27;295(13):4065-4078. doi: 10.1074/jbc.RA119.009827. Epub 2019 Nov 5. J Biol Chem. 2020. PMID: 31690629 Free PMC article.

6

The HIF complex recruits the histone methyltransferase SET1B to activate specific hypoxia-inducible genes.

Ortmann BM, Burrows N, Lobb IT, Arnaiz E, Wit N, Bailey PSJ, Jordon LH, Lombardi O, Peñalver A, McCaffrey J, Seear R, Mole DR, Ratcliffe PJ, Maxwell PH, Nathan JA. Ortmann BM, et al. Among authors: lombardi o. Nat Genet. 2021 Jul;53(7):1022-1035. doi: 10.1038/s41588-021-00887-y. Epub 2021 Jun 21. Nat Genet. 2021. PMID: 34155378 Free PMC article.

7

mRNA Cap Methyltransferase, RNMT-RAM, Promotes RNA Pol II-Dependent Transcription.

Varshney D, Lombardi O, Schweikert G, Dunn S, Suska O, Cowling VH. Varshney D, et al. Among authors: lombardi o. Cell Rep. 2018 May 1;23(5):1530-1542. doi: 10.1016/j.celrep.2018.04.004. Cell Rep. 2018. PMID: 29719263 Free PMC article.

8

Dynamic gating of perceptual flexibility by non-classically responsive cortical neurons.

Toth J, Sidleck B, Lombardi O, Hou T, Eldo A, Kerlin M, Zeng X, Saeed D, Agarwal P, Leonard D, Andrino L, Inbar T, Malina M, Insanally MN. Toth J, et al. Among authors: lombardi o. Res Sq [Preprint]. 2024 Jul 23:rs.3.rs-4650869. doi: 10.21203/rs.3.rs-4650869/v1. Res Sq. 2024. PMID: 39108496 Free PMC article. Preprint.

9

A Review of the Concept of Time Reversal and the Direction of Time.

López C, Lombardi O. López C, et al. Among authors: lombardi o. Entropy (Basel). 2024 Jun 30;26(7):563. doi: 10.3390/e26070563. Entropy (Basel). 2024. PMID: 39056925 Free PMC article.

10

Contributions of cortical neuron firing patterns, synaptic connectivity, and plasticity to task performance.

Insanally MN, Albanna BF, Toth J, DePasquale B, Fadaei SS, Gupta T, Lombardi O, Kuchibhotla K, Rajan K, Froemke RC. Insanally MN, et al. Among authors: lombardi o. Nat Commun. 2024 Jul 17;15(1):6023. doi: 10.1038/s41467-024-49895-6. Nat Commun. 2024. PMID: 39019848 Free PMC article.

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