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Page 1
Chromatin conformation, gene transcription, and nucleosome remodeling as an emergent system.
Almassalha LM, Carignano M, Liwag EP, Li WS, Gong R, Acosta N, Dunton CL, Gonzalez PC, Carter LM, Kakkaramadam R, Kröger M, MacQuarrie KL, Frederick J, Ye IC, Su P, Kuo T, Medina KI, Pritchard JA, Skol A, Nap R, Kanemaki M, Dravid V, Szleifer I, Backman V. Almassalha LM, et al. Among authors: backman v. Sci Adv. 2025 Jan 10;11(2):eadq6652. doi: 10.1126/sciadv.adq6652. Epub 2025 Jan 10. Sci Adv. 2025. PMID: 39792661 Free PMC article.
Disordered chromatin packing regulates phenotypic plasticity.
Virk RKA, Wu W, Almassalha LM, Bauer GM, Li Y, VanDerway D, Frederick J, Zhang D, Eshein A, Roy HK, Szleifer I, Backman V. Virk RKA, et al. Among authors: backman v. Sci Adv. 2020 Jan 8;6(2):eaax6232. doi: 10.1126/sciadv.aax6232. eCollection 2020 Jan. Sci Adv. 2020. PMID: 31934628 Free PMC article.
Physical and data structure of 3D genome.
Huang K, Li Y, Shim AR, Virk RKA, Agrawal V, Eshein A, Nap RJ, Almassalha LM, Backman V, Szleifer I. Huang K, et al. Among authors: backman v. Sci Adv. 2020 Jan 10;6(2):eaay4055. doi: 10.1126/sciadv.aay4055. eCollection 2020 Jan. Sci Adv. 2020. PMID: 31950084 Free PMC article.
Nanoscale chromatin imaging and analysis platform bridges 4D chromatin organization with molecular function.
Li Y, Eshein A, Virk RKA, Eid A, Wu W, Frederick J, VanDerway D, Gladstein S, Huang K, Shim AR, Anthony NM, Bauer GM, Zhou X, Agrawal V, Pujadas EM, Jain S, Esteve G, Chandler JE, Nguyen TQ, Bleher R, de Pablo JJ, Szleifer I, Dravid VP, Almassalha LM, Backman V. Li Y, et al. Among authors: backman v. Sci Adv. 2021 Jan 1;7(1):eabe4310. doi: 10.1126/sciadv.abe4310. Print 2021 Jan. Sci Adv. 2021. PMID: 33523864 Free PMC article.
Formamide denaturation of double-stranded DNA for fluorescence in situ hybridization (FISH) distorts nanoscale chromatin structure.
Shim AR, Frederick J, Pujadas EM, Kuo T, Ye IC, Pritchard JA, Dunton CL, Gonzalez PC, Acosta N, Jain S, Anthony NM, Almassalha LM, Szleifer I, Backman V. Shim AR, et al. Among authors: backman v. PLoS One. 2024 May 28;19(5):e0301000. doi: 10.1371/journal.pone.0301000. eCollection 2024. PLoS One. 2024. PMID: 38805476 Free PMC article.
Leveraging chromatin packing domains to target chemoevasion in vivo.
Frederick J, Virk RKA, Ye IC, Almassalha LM, Wodarcyk GM, VanDerway D, Gonzalez PC, Nap RJ, Agrawal V, Anthony NM, Carinato J, Li WS, Dunton CL, Medina KI, Kakkaramadam R, Jain S, Shahabi S, Ameer G, Szleifer IG, Backman V. Frederick J, et al. Among authors: backman v. bioRxiv [Preprint]. 2024 Nov 15:2024.11.14.623612. doi: 10.1101/2024.11.14.623612. bioRxiv. 2024. PMID: 39605341 Free PMC article. Preprint.
Macromolecular crowding as a regulator of gene transcription.
Matsuda H, Putzel GG, Backman V, Szleifer I. Matsuda H, et al. Among authors: backman v. Biophys J. 2014 Apr 15;106(8):1801-10. doi: 10.1016/j.bpj.2014.02.019. Biophys J. 2014. PMID: 24739179 Free PMC article.
269 results