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Integrin-activating Yersinia protein Invasin sustains long-term expansion of primary epithelial cells as 2D organoid sheets.
Wijnakker JJAPM, van Son GJF, Krueger D, van de Wetering WJ, Lopez-Iglesias C, Schreurs R, van Rijt F, Lim S, Lin L, Peters PJ, Isberg RR, Janda CY, de Lau W, Clevers H. Wijnakker JJAPM, et al. Among authors: isberg rr. Proc Natl Acad Sci U S A. 2025 Jan 7;122(1):e2420595121. doi: 10.1073/pnas.2420595121. Epub 2024 Dec 30. Proc Natl Acad Sci U S A. 2025. PMID: 39793062 Free PMC article.
Identification of Determinants that Allow Maintenance of High-Level Fluoroquinolone Resistance in Acinetobacter baumannii.
Hamami E, Huo W, Hernandez-Bird J, Castaneda A, Bai J, Syal S, Ortiz-Marquez JC, van Opijnen T, Geisinger E, Isberg RR. Hamami E, et al. Among authors: isberg rr. bioRxiv [Preprint]. 2024 Oct 16:2023.10.03.560562. doi: 10.1101/2023.10.03.560562. bioRxiv. 2024. Update in: mBio. 2025 Jan 8;16(1):e0322124. doi: 10.1128/mbio.03221-24 PMID: 38645180 Free PMC article. Updated. Preprint.
Sde Proteins Coordinate Ubiquitin Utilization and Phosphoribosylation to Establish and Maintain the Legionella Replication Vacuole.
Kotewicz KM, Zhang M, Kim S, Martin MS, Chowdhury AR, Tai A, Scheck RA, Isberg RR. Kotewicz KM, et al. Among authors: isberg rr. bioRxiv [Preprint]. 2024 Jul 16:2023.09.07.553534. doi: 10.1101/2023.09.07.553534. bioRxiv. 2024. Update in: Nat Commun. 2024 Aug 30;15(1):7479. doi: 10.1038/s41467-024-51272-2 PMID: 38645023 Free PMC article. Updated. Preprint.
Massively parallel combination screen reveals small molecule sensitization of antibiotic-resistant Gram-negative ESKAPE pathogens.
Tse MW, Zhu M, Peters B, Hamami E, Chen J, Davis KP, Nitz S, Weller J, Warrier T, Hunt DK, Morales Y, Kawate T, Gaulin JL, Come JH, Hernandez-Bird J, Huo W, Neisewander I, Kiessling LL, Hung DT, Mecsas J, Aldridge BB, Isberg RR, Blainey PC. Tse MW, et al. Among authors: isberg rr. bioRxiv [Preprint]. 2024 Mar 26:2024.03.26.586803. doi: 10.1101/2024.03.26.586803. bioRxiv. 2024. PMID: 38585790 Free PMC article. Preprint.
Genetic evidence for a regulated cysteine protease catalytic triad in LegA7, a Legionella pneumophila protein that impinges on a stress response pathway.
Hershkovitz D, Chen EJ, Ensminger AW, Dugan AS, Conway KT, Joyce AC, Segal G, Isberg RR. Hershkovitz D, et al. Among authors: isberg rr. bioRxiv [Preprint]. 2024 Jun 25:2024.03.17.585421. doi: 10.1101/2024.03.17.585421. bioRxiv. 2024. Update in: mSphere. 2024 Sep 25;9(9):e0022224. doi: 10.1128/msphere.00222-24 PMID: 38562771 Free PMC article. Updated. Preprint.
207 results