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Design, Structure-Activity Relationships, and Computational Modeling Studies of a Series of α-Helix Biased, Ultra-Short Glucagon-like Peptide-1 Receptor Agonists.
Sawyer JR, Audie JA, Swanson J, Diller D, Santiago S, Gribkoff VK, Ackerman A, Hruby VJ, Gobbo G, Bellucci MA, Glauser WA, Pentelute BL, Sawyer TK. Sawyer JR, et al. Among authors: hruby vj. Molecules. 2024 Dec 24;30(1):12. doi: 10.3390/molecules30010012. Molecules. 2024. PMID: 39795070 Free PMC article.
CLIPSing Melanotan-II to Discover Multiple Functionally Selective hMCR Agonists.
Tomassi S, Dimmito MP, Cai M, D'Aniello A, Del Bene A, Messere A, Liu Z, Zhu T, Hruby VJ, Stefanucci A, Cosconati S, Mollica A, Di Maro S. Tomassi S, et al. Among authors: hruby vj. J Med Chem. 2022 Mar 10;65(5):4007-4017. doi: 10.1021/acs.jmedchem.1c01848. Epub 2022 Feb 21. J Med Chem. 2022. PMID: 35188390
751 results