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The C. elegans homolog of Sjögren's Syndrome Nuclear Antigen 1 is required for the structural integrity of the centriole and bipolar mitotic spindle assembly.
Pfister JA, Agostini L, Bournonville L, Sankaralingam P, Bell ZG, Hamel V, Guichard P, Biertümpfel C, Mizuno N, O'Connell KF. Pfister JA, et al. Among authors: o connell kf. bioRxiv [Preprint]. 2024 Oct 4:2024.10.03.616528. doi: 10.1101/2024.10.03.616528. bioRxiv. 2024. PMID: 39803516 Free PMC article. Preprint.
The chromatin remodeling protein CHD-1 and the EFL-1/DPL-1 transcription factor cooperatively down regulate CDK-2 to control SAS-6 levels and centriole number.
Iyer J, Gentry LK, Bergwell M, Smith A, Guagliardo S, Kropp PA, Sankaralingam P, Liu Y, Spooner E, Bowerman B, O'Connell KF. Iyer J, et al. Among authors: o connell kf. PLoS Genet. 2022 Apr 4;18(4):e1009799. doi: 10.1371/journal.pgen.1009799. eCollection 2022 Apr. PLoS Genet. 2022. PMID: 35377871 Free PMC article.
Centrioles: some self-assembly required.
Song MH, Miliaras NB, Peel N, O'Connell KF. Song MH, et al. Curr Opin Cell Biol. 2008 Dec;20(6):688-93. doi: 10.1016/j.ceb.2008.09.001. Epub 2008 Oct 25. Curr Opin Cell Biol. 2008. PMID: 18840522 Free PMC article. Review.
34 results