Meng T-C - Search Results

1

Gut colonization of Bacteroides plebeius suppresses colitis-associated colon cancer development.

Chen H-L, Hu P-Y, Chen C-S, Lin W-H, Hsu DK, Liu F-T, Meng T-C. Chen H-L, et al. Among authors: meng t c. Microbiol Spectr. 2025 Jan 13:e0259924. doi: 10.1128/spectrum.02599-24. Online ahead of print. Microbiol Spectr. 2025. PMID: 39804065 Free article.

2

Pharmacological inhibition of the Src homology phosphatase 2 confers partial protection in a mouse model of alcohol-associated liver disease.

Hsu MF, Koike S, Chen CS, Najjar SM, Meng TC, Haj FG. Hsu MF, et al. Among authors: meng tc. Biomed Pharmacother. 2024 Jun;175:116590. doi: 10.1016/j.biopha.2024.116590. Epub 2024 Apr 22. Biomed Pharmacother. 2024. PMID: 38653109 Free article.

3

Protein tyrosine phosphatase 1B is a regulator of alpha-actinin4 in the glomerular podocyte.

Hsu MF, Ito Y, Singh JP, Hsu SF, Wells A, Jen KY, Meng TC, Haj FG. Hsu MF, et al. Among authors: meng tc. Biochim Biophys Acta Mol Cell Res. 2024 Jan;1871(1):119590. doi: 10.1016/j.bbamcr.2023.119590. Epub 2023 Sep 18. Biochim Biophys Acta Mol Cell Res. 2024. PMID: 37730132 Free PMC article.

4

High Density of N- and O-Glycosylation Shields and Defines the Structural Dynamics of the Intrinsically Disordered Ectodomain of Receptor-type Protein Tyrosine Phosphatase Alpha.

Chien YC, Wang YS, Sridharan D, Kuo CW, Chien CT, Uchihashi T, Kato K, Angata T, Meng TC, Hsu SD, Khoo KH. Chien YC, et al. Among authors: meng tc. JACS Au. 2023 Jun 13;3(7):1864-1875. doi: 10.1021/jacsau.3c00124. eCollection 2023 Jul 24. JACS Au. 2023. PMID: 37502146 Free PMC article.

5

Application of hybrid biophysical-biochemical methods to unravel the molecular basis for auto-inhibition and activation of protein tyrosine phosphatase TCPTP/PTPN2.

Singh JP, Chen YY, Huang YT, Hsu SD, Meng TC. Singh JP, et al. Among authors: meng tc. Methods Enzymol. 2023;682:351-374. doi: 10.1016/bs.mie.2022.09.008. Epub 2023 Jan 4. Methods Enzymol. 2023. PMID: 36948707

6

Active-site cysteine 215 sulfonation targets protein tyrosine phosphatase PTP1B for Cullin1 E3 ligase-mediated degradation.

Yang CY, Yang CF, Tang XF, Machado LESF, Singh JP, Peti W, Chen CS, Meng TC. Yang CY, et al. Among authors: meng tc. Free Radic Biol Med. 2023 Jan;194:147-159. doi: 10.1016/j.freeradbiomed.2022.11.041. Epub 2022 Nov 30. Free Radic Biol Med. 2023. PMID: 36462629

7

Psychosocial outcomes of repeated treatment of seizure clusters with midazolam nasal spray: Results of a phase 3, open-label extension trial.

Meng TC, Szaflarski JP, Chen L, Brunnert M, Campos R, Van Ess P, Pullman WE, Fakhoury T. Meng TC, et al. Epilepsy Behav. 2023 Jan;138:108989. doi: 10.1016/j.yebeh.2022.108989. Epub 2022 Nov 18. Epilepsy Behav. 2023. PMID: 36410152 Free article. Clinical Trial.

8

The catalytic activity of TCPTP is auto-regulated by its intrinsically disordered tail and activated by Integrin alpha-1.

Singh JP, Li Y, Chen YY, Hsu SD, Page R, Peti W, Meng TC. Singh JP, et al. Among authors: meng tc. Nat Commun. 2022 Jan 10;13(1):94. doi: 10.1038/s41467-021-27633-6. Nat Commun. 2022. PMID: 35013194 Free PMC article.

9

Crystal Structure of TCPTP Unravels an Allosteric Regulatory Role of Helix α7 in Phosphatase Activity.

Singh JP, Lin MJ, Hsu SF, Peti W, Lee CC, Meng TC. Singh JP, et al. Among authors: meng tc. Biochemistry. 2021 Dec 28;60(51):3856-3867. doi: 10.1021/acs.biochem.1c00519. Epub 2021 Dec 15. Biochemistry. 2021. PMID: 34910875

10

Safety and efficacy of midazolam nasal spray for the treatment of intermittent bouts of increased seizure activity in the epilepsy monitoring unit: A double-blind, randomized, placebo-controlled trial.

Spencer DC, Sinha SR, Choi EJ, Cleveland JM, King A, Meng TC, Pullman WE, Sequeira DJ, Van Ess PJ, Wheless JW. Spencer DC, et al. Among authors: meng tc. Epilepsia. 2020 Nov;61(11):2415-2425. doi: 10.1111/epi.16704. Epub 2020 Nov 2. Epilepsia. 2020. PMID: 33140403 Clinical Trial.

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