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Page 1
High cellular plasticity state of medulloblastoma local recurrence and distant dissemination.
Liu H, Zhang J, Wang Z, Wang W, Han D, Chen X, Su Y, Zhang J, Daniels C, Saulnier O, Wang ZJ, Gu C, Liu F, Deng K, Wang D, Feng Z, Zhao Y, Jiang Y, Gao Y, Liu Z, Ma M, Li Y, Zhao Z, Yuan H, Sun Y, Shi Y, Yang T, Li W, Qi X, Duan Z, Zhang J, Zhang M, Yu C, Jin W, Yu X, Tian Y, Li S, Li C, Taylor MD, Li J, Liu YQ, Qiu X, Jiang T. Liu H, et al. Among authors: saulnier o. Cell Rep Med. 2025 Jan 6:101914. doi: 10.1016/j.xcrm.2024.101914. Online ahead of print. Cell Rep Med. 2025. PMID: 39809264 Free article.
Systematic transcriptomic analysis of childhood medulloblastoma identifies N6- methyladenosine-dependent lncRNA signatures associated with molecular subtype, immune cell infiltration, and prognosis.
Joshi K, Yuan M, Katsushima K, Saulnier O, Ray A, Amankwah E, Stapleton S, Jallo G, Taylor MD, Eberhart CG, Perera RJ. Joshi K, et al. Among authors: saulnier o. Res Sq [Preprint]. 2024 Sep 2:rs.3.rs-4810070. doi: 10.21203/rs.3.rs-4810070/v1. Res Sq. 2024. Update in: Acta Neuropathol Commun. 2024 Aug 28;12(1):138. doi: 10.1186/s40478-024-01848-2 PMID: 39281885 Free PMC article. Updated. Preprint.
Insights on Future Directions in Cancer Research from the AACR NextGen Stars.
Cañadas I, Casirati G, Houlahan KE, Maxwell KN, Mehta A, Parolia A, Saulnier O, Taylor AM, Thomas CE, Vázquez-García I. Cañadas I, et al. Among authors: saulnier o. Cancer Discov. 2024 Sep 4;14(9):1584-1589. doi: 10.1158/2159-8290.CD-24-0774. Cancer Discov. 2024. PMID: 39228299 No abstract available.
Systematic transcriptomic analysis of childhood medulloblastoma identifies N6-methyladenosine-dependent lncRNA signatures associated with molecular subtype, immune cell infiltration, and prognosis.
Joshi K, Yuan M, Katsushima K, Saulnier O, Ray A, Amankwah E, Stapleton S, Jallo G, Taylor MD, Eberhart CG, Perera RJ. Joshi K, et al. Among authors: saulnier o. Acta Neuropathol Commun. 2024 Aug 28;12(1):138. doi: 10.1186/s40478-024-01848-2. Acta Neuropathol Commun. 2024. PMID: 39198884 Free PMC article.
A group 3 medulloblastoma stem cell program is maintained by OTX2-mediated alternative splicing.
Saulnier O, Zagozewski J, Liang L, Hendrikse LD, Layug P, Gordon V, Aldinger KA, Haldipur P, Borlase S, Coudière-Morrison L, Cai T, Martell E, Gonzales NM, Palidwor G, Porter CJ, Richard S, Sharif T, Millen KJ, Doble BW, Taylor MD, Werbowetski-Ogilvie TE. Saulnier O, et al. Nat Cell Biol. 2024 Aug;26(8):1233-1246. doi: 10.1038/s41556-024-01460-5. Epub 2024 Jul 18. Nat Cell Biol. 2024. PMID: 39025928 Free PMC article.
Early rhombic lip Protogenin+ve stem cells in a human-specific neurovascular niche initiate and maintain group 3 medulloblastoma.
Visvanathan A, Saulnier O, Chen C, Haldipur P, Orisme W, Delaidelli A, Shin S, Millman J, Bryant A, Abeysundara N, Wu X, Hendrikse LD, Patil V, Bashardanesh Z, Golser J, Livingston BG, Nakashima T, Funakoshi Y, Ong W, Rasnitsyn A, Aldinger KA, Richman CM, Van Ommeren R, Lee JJY, Ly M, Vladoiu MC, Kharas K, Balin P, Erickson AW, Fong V, Zhang J, Suárez RA, Wang H, Huang N, Pallota JG, Douglas T, Haapasalo J, Razavi F, Silvestri E, Sirbu O, Worme S, Kameda-Smith MM, Wu X, Daniels C, MichaelRaj AK, Bhaduri A, Schramek D, Suzuki H, Garzia L, Ahmed N, Kleinman CL, Stein LD, Dirks P, Dunham C, Jabado N, Rich JN, Li W, Sorensen PH, Wechsler-Reya RJ, Weiss WA, Millen KJ, Ellison DW, Dimitrov DS, Taylor MD. Visvanathan A, et al. Among authors: saulnier o. Cell. 2024 Aug 22;187(17):4733-4750.e26. doi: 10.1016/j.cell.2024.06.011. Epub 2024 Jul 5. Cell. 2024. PMID: 38971152 Free PMC article.
A therapeutically targetable positive feedback loop between lnc-HLX-2-7, HLX, and MYC that promotes group 3 medulloblastoma.
Katsushima K, Joshi K, Yuan M, Romero B, Batish M, Stapleton S, Jallo G, Kolanthai E, Seal S, Saulnier O, Taylor MD, Wechsler-Reya RJ, Eberhart CG, Perera RJ. Katsushima K, et al. Among authors: saulnier o. Cell Rep. 2024 Mar 26;43(3):113938. doi: 10.1016/j.celrep.2024.113938. Epub 2024 Mar 8. Cell Rep. 2024. PMID: 38460130 Free PMC article.
Lymphatic endothelial-like cells promote glioblastoma stem cell growth through cytokine-driven cholesterol metabolism.
Zhao L, Qiu Z, Yang Z, Xu L, Pearce TM, Wu Q, Yang K, Li F, Saulnier O, Fei F, Yu H, Gimple RC, Varadharajan V, Liu J, Hendrikse LD, Fong V, Wang W, Zhang J, Lv D, Lee D, Lehrich BM, Jin C, Ouyang L, Dixit D, Wu H, Wang X, Sloan AE, Wang X, Huan T, Mark Brown J, Goldman SA, Taylor MD, Zhou S, Rich JN. Zhao L, et al. Among authors: saulnier o. Nat Cancer. 2024 Jan;5(1):147-166. doi: 10.1038/s43018-023-00658-0. Epub 2024 Jan 3. Nat Cancer. 2024. PMID: 38172338
miRNA-211 maintains metabolic homeostasis in medulloblastoma through its target gene long-chain acyl-CoA synthetase 4.
Yuan M, Mahmud I, Katsushima K, Joshi K, Saulnier O, Pokhrel R, Lee B, Liyanage W, Kunhiraman H, Stapleton S, Gonzalez-Gomez I, Kannan RM, Eisemann T, Kolanthai E, Seal S, Garrett TJ, Abbasi S, Bockley K, Hanes J, Chapagain P, Jallo G, Wechsler-Reya RJ, Taylor MD, Eberhart CG, Ray A, Perera RJ. Yuan M, et al. Among authors: saulnier o. Acta Neuropathol Commun. 2023 Dec 19;11(1):203. doi: 10.1186/s40478-023-01684-w. Acta Neuropathol Commun. 2023. PMID: 38115140 Free PMC article.
27 results