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Host-microbe multi-omics and succinotype profiling have prognostic value for future relapse in patients with inflammatory bowel disease.
O'Sullivan J, Patel S, Leventhal GE, Fitzgerald RS, Laserna-Mendieta EJ, Huseyin CE, Konstantinidou N, Rutherford E, Lavelle A, Dabbagh K, DeSantis TZ, Shanahan F, Temko A, Iwai S, Claesson MJ. O'Sullivan J, et al. Among authors: leventhal ge. Gut Microbes. 2025 Dec;17(1):2450207. doi: 10.1080/19490976.2025.2450207. Epub 2025 Jan 15. Gut Microbes. 2025. PMID: 39812341 Free article.
Efficacy and Safety of Anthocyanin-Rich Extract in Patients with Ulcerative Colitis: A Randomized Controlled Trial.
Biedermann L, Doulberis M, Schreiner P, Nielsen OH, The FO, Brand S, Burk S, Hruz P, Juillerat P, Krieger-Grübel C, Leu K, Leventhal GE, Misselwitz B, Scharl S, Schoepfer A, Seibold F, Herfarth H, Rogler G. Biedermann L, et al. Among authors: leventhal ge. Nutrients. 2024 Dec 4;16(23):4197. doi: 10.3390/nu16234197. Nutrients. 2024. PMID: 39683589 Free PMC article. Clinical Trial.
Targeted hypermutation of putative antigen sensors in multicellular bacteria.
Doré H, Eisenberg AR, Junkins EN, Leventhal GE, Ganesh A, Cordero OX, Paul BG, Valentine DL, O'Malley MA, Wilbanks EG. Doré H, et al. Among authors: leventhal ge. Proc Natl Acad Sci U S A. 2024 Feb 27;121(9):e2316469121. doi: 10.1073/pnas.2316469121. Epub 2024 Feb 14. Proc Natl Acad Sci U S A. 2024. PMID: 38354254 Free PMC article.
Co-cultivation is a powerful approach to produce a robust functionally designed synthetic consortium as a live biotherapeutic product (LBP).
Kurt F, Leventhal GE, Spalinger MR, Anthamatten L, Rogalla von Bieberstein P, Menzi C, Reichlin M, Meola M, Rosenthal F, Rogler G, Lacroix C, de Wouters T. Kurt F, et al. Among authors: leventhal ge. Gut Microbes. 2023 Jan-Dec;15(1):2177486. doi: 10.1080/19490976.2023.2177486. Gut Microbes. 2023. PMID: 36794804 Free PMC article.
Novel integrative elements and genomic plasticity in ocean ecosystems.
Hackl T, Laurenceau R, Ankenbrand MJ, Bliem C, Cariani Z, Thomas E, Dooley KD, Arellano AA, Hogle SL, Berube P, Leventhal GE, Luo E, Eppley JM, Zayed AA, Beaulaurier J, Stepanauskas R, Sullivan MB, DeLong EF, Biller SJ, Chisholm SW. Hackl T, et al. Among authors: leventhal ge. Cell. 2023 Jan 5;186(1):47-62.e16. doi: 10.1016/j.cell.2022.12.006. Cell. 2023. PMID: 36608657 Free article.
Microbiome-based interventions to modulate gut ecology and the immune system.
Hitch TCA, Hall LJ, Walsh SK, Leventhal GE, Slack E, de Wouters T, Walter J, Clavel T. Hitch TCA, et al. Among authors: leventhal ge. Mucosal Immunol. 2022 Jun;15(6):1095-1113. doi: 10.1038/s41385-022-00564-1. Epub 2022 Sep 30. Mucosal Immunol. 2022. PMID: 36180583 Free PMC article. Review.
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