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Page 1
Host-microbe multiomic profiling identifies distinct COVID-19 immune dysregulation in solid organ transplant recipients.
Pickering H, Schaenman J, Phan HV, Maguire C, Tsitsiklis A, Rouphael N, Higuita NIA, Atkinson MA, Brakenridge S, Fung M, Messer W; IMPACC Network; Salehi-Rad R, Altman MC, Becker PM, Bosinger SE, Eckalbar W, Hoch A, Doni Jayavelu N, Kim-Schulze S, Jenkins M, Kleinstein SH, Krammer F, Maecker HT, Ozonoff A, Diray-Arce J, Shaw A, Baden L, Levy O, Reed EF, Langelier CR. Pickering H, et al. Nat Commun. 2025 Jan 10;16(1):586. doi: 10.1038/s41467-025-55823-z. Nat Commun. 2025. PMID: 39794319 Free PMC article.
Author Correction: Dissection of artifactual and confounding glial signatures by single-cell sequencing of mouse and human brain.
Marsh SE, Walker AJ, Kamath T, Dissing-Olesen L, Hammond TR, de Soysa TY, Young AMH, Murphy S, Abdulraouf A, Nadaf N, Dufort C, Walker AC, Lucca LE, Kozareva V, Vanderburg C, Hong S, Bulstrode H, Hutchinson PJ, Gaffney DJ, Hafler DA, Franklin RJM, Macosko EZ, Stevens B. Marsh SE, et al. Among authors: hafler da. Nat Neurosci. 2025 Jan;28(1):215. doi: 10.1038/s41593-024-01855-5. Nat Neurosci. 2025. PMID: 39672966 Free PMC article. No abstract available.
Unraveling SARS-CoV-2 Host-Response Heterogeneity through Longitudinal Molecular Subtyping.
Wang K, Nie Y, Maguire C, Syphurs C, Sheen H, Karoly M, Lapp L, Gygi JP, Jayavelu ND, Patel RK, Hoch A; IMPACC Network; Corry D, Kheradmand F, McComsey GA, Fernandez-Sesma A, Simon V, Metcalf JP, Higuita NIA, Messer WB, Davis MM, Nadeau KC, Kraft M, Bime C, Schaenman J, Erle D, Calfee CS, Atkinson MA, Brackenridge SC, Hafler DA, Shaw A, Rahman A, Hough CL, Geng LN, Ozonoff A, Haddad EK, Reed EF, van Bakel H, Kim-Schultz S, Krammer F, Wilson M, Eckalbar W, Bosinger S, Langelier CR, Sekaly RP, Montgomery RR, Maecker HT, Krumholz H, Melamed E, Steen H, Pulendran B, Augustine AD, Cairns CB, Rouphael N, Becker PM, Fourati S, Shannon CP, Smolen KK, Peters B, Kleinstein SH, Levy O, Altman MC, Iwasaki A, Diray-Arce J, Ehrlich LIR, Guan L. Wang K, et al. Among authors: hafler da. bioRxiv [Preprint]. 2024 Nov 25:2024.11.22.624784. doi: 10.1101/2024.11.22.624784. bioRxiv. 2024. PMID: 39651165 Free PMC article. Preprint.
Circulating tumor-reactive KIR+CD8+ T cells suppress anti-tumor immunity in patients with melanoma.
Lu BY, Lucca LE, Lewis W, Wang J, Nogueira CV, Heer S, Rayon-Estrada V, Axisa PP, Reeves SM, Buitrago-Pocasangre NC, Pham GH, Kojima ML, Wei W, Aizenbud L, Bacchiocchi A, Zhang L, Walewski JJ, Chiang V, Olino K, Clune J, Halaban R, Kluger Y, Coyle AJ, Kisielow J, Obermair FJ, Kluger HM, Hafler DA. Lu BY, et al. Among authors: hafler da. Nat Immunol. 2025 Jan;26(1):82-91. doi: 10.1038/s41590-024-02023-4. Epub 2024 Nov 28. Nat Immunol. 2025. PMID: 39609626
Chronic Viral Reactivation and Associated Host Immune Response and Clinical Outcomes in Acute COVID-19 and Post-Acute Sequelae of COVID-19.
Maguire C, Chen J, Rouphael N, Pickering H, Phan HV, Glascock A, Chu V, Dandekar R, Corry D, Kheradmand F, Baden LR, Selaky R, McComsey GA, Haddad EK, Cairns CB, Pulendran B, Fernandez-Sesma A, Simon V, Metcalf JP, Higuita NIA, Messer WB, David MM, Nadeau KC, Kraft M, Bime C, Schaenman J, Erle D, Calfee CS, Atkinson MA, Brackenridge SC, Ehrlich LIR, Montgomery RR, Shaw AC, Hough CL, Geng LN, Hafler DA, Augustine AD, Becker PM, Peters B, Ozonoff A, Kim-Schulze SH, Krammer F, Bosinger S, Eckalbar W, Altman MC, Wilson M, Guan L, Kleinstein SH; IMPACC Network; Smolen KK, Reed EF, Levy O, Maecker H, Hunt P, Steen H, Diray-Arce J, Langelier CR, Melamed E. Maguire C, et al. Among authors: hafler da. bioRxiv [Preprint]. 2024 Nov 16:2024.11.14.622799. doi: 10.1101/2024.11.14.622799. bioRxiv. 2024. PMID: 39605478 Free PMC article. Preprint.
Single-cell transcriptomic and proteomic analysis of Parkinson's disease brains.
Zhu B, Park JM, Coffey SR, Russo A, Hsu IU, Wang J, Su C, Chang R, Lam TT, Gopal PP, Ginsberg SD, Zhao H, Hafler DA, Chandra SS, Zhang L. Zhu B, et al. Among authors: hafler da. Sci Transl Med. 2024 Oct 30;16(771):eabo1997. doi: 10.1126/scitranslmed.abo1997. Epub 2024 Oct 30. Sci Transl Med. 2024. PMID: 39475571
An autoimmune transcriptional circuit drives FOXP3+ regulatory T cell dysfunction.
Sumida TS, Lincoln MR, He L, Park Y, Ota M, Oguchi A, Son R, Yi A, Stillwell HA, Leissa GA, Fujio K, Murakawa Y, Kulminski AM, Epstein CB, Bernstein BE, Kellis M, Hafler DA. Sumida TS, et al. Among authors: hafler da. Sci Transl Med. 2024 Aug 28;16(762):eadp1720. doi: 10.1126/scitranslmed.adp1720. Epub 2024 Aug 28. Sci Transl Med. 2024. PMID: 39196959
466 results