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MnSOD non-acetylation mimic knock-in mice exhibit dilated cardiomyopathy.
Schell JR, Wei SJ, Zhang J, Trevino R Jr, Chen WH, Aguilar L, Qian W, Corbett CW, Jiang H, Dong FF, Chocron ES, Nazarullah A, Chang J, Flanagan ME, Glatt V, Dikalov S, Munkácsy E, Horikoshi N, Gius D. Schell JR, et al. Among authors: chocron es. Free Radic Biol Med. 2025 Jan 15:S0891-5849(25)00028-0. doi: 10.1016/j.freeradbiomed.2025.01.028. Online ahead of print. Free Radic Biol Med. 2025. PMID: 39824446
Ketogenic diet induces p53-dependent cellular senescence in multiple organs.
Wei SJ, Schell JR, Chocron ES, Varmazyad M, Xu G, Chen WH, Martinez GM, Dong FF, Sreenivas P, Trevino R Jr, Jiang H, Du Y, Saliba A, Qian W, Lorenzana B, Nazarullah A, Chang J, Sharma K, Munkácsy E, Horikoshi N, Gius D. Wei SJ, et al. Among authors: chocron es. Sci Adv. 2024 May 17;10(20):eado1463. doi: 10.1126/sciadv.ado1463. Epub 2024 May 17. Sci Adv. 2024. PMID: 38758782 Free PMC article.
Mitochondrial ACSS1-K635 acetylation knock-in mice exhibit altered metabolism, cell senescence, and nonalcoholic fatty liver disease.
Xu G, Quan S, Schell J, Gao Y, Varmazyad M, Sreenivas P, Cruz D, Jiang H, Pan M, Han X, Palavicini JP, Zhao P, Sun X, Marchant ED, Rasmussen BB, Li G, Katsumura S, Morita M, Munkácsy E, Horikoshi N, Chocron ES, Gius D. Xu G, et al. Among authors: chocron es. Sci Adv. 2024 May 17;10(20):eadj5942. doi: 10.1126/sciadv.adj5942. Epub 2024 May 17. Sci Adv. 2024. PMID: 38758779 Free PMC article.
Genetic and pharmacologic proteasome augmentation ameliorates Alzheimer's-like pathology in mouse and fly APP overexpression models.
Chocron ES, Munkácsy E, Kim HS, Karpowicz P, Jiang N, Van Skike CE, DeRosa N, Banh AQ, Palavicini JP, Wityk P, Kalinowski L, Galvan V, Osmulski PA, Jankowska E, Gaczynska M, Pickering AM. Chocron ES, et al. Sci Adv. 2022 Jun 10;8(23):eabk2252. doi: 10.1126/sciadv.abk2252. Epub 2022 Jun 8. Sci Adv. 2022. PMID: 35675410 Free PMC article.
PrimPol, an archaic primase/polymerase operating in human cells.
García-Gómez S, Reyes A, Martínez-Jiménez MI, Chocrón ES, Mourón S, Terrados G, Powell C, Salido E, Méndez J, Holt IJ, Blanco L. García-Gómez S, et al. Among authors: chocron es. Mol Cell. 2013 Nov 21;52(4):541-53. doi: 10.1016/j.molcel.2013.09.025. Epub 2013 Oct 24. Mol Cell. 2013. PMID: 24207056 Free PMC article.
13 results