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Preliminary effects of oral ANS-6637, an ALDH2 inhibitor, on cue-induced craving, safety and alcohol consumption among adults with alcohol use disorder: a proof-of-concept, randomized, human laboratory trial.
O'Malley SS, Miranda R Jr, Book SW, Chun TH, Liss T, Malcolm RJ, Muvvala SB, Padovano HT, Schacht JP, Blackburn B, Diamond I, Ransom J, Ryan ML, Falk DE, Litten RZ. O'Malley SS, et al. Among authors: schacht jp. Alcohol Alcohol. 2025 Jan 19;60(2):agaf001. doi: 10.1093/alcalc/agaf001. Alcohol Alcohol. 2025. PMID: 39829301 Clinical Trial.
Effects of a novel GABA-B positive allosteric modulator, ASP8062, on alcohol cue-elicited craving and naturalistic alcohol consumption in a multisite randomized, double-blind, placebo-controlled trial.
Schacht JP, Ray LA, Miranda R Jr, Falk DE, Ryan ML, Sakai JT, Miotto K, Chun T, Scott C, Ransom J, Alsharif N, Ito M, Litten RZ. Schacht JP, et al. Alcohol Clin Exp Res (Hoboken). 2024 Dec;48(12):2352-2363. doi: 10.1111/acer.15468. Epub 2024 Dec 2. Alcohol Clin Exp Res (Hoboken). 2024. PMID: 39623527
56 results