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129 results

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Page 1
Glioma-induced alterations in excitatory neurons are reversed by mTOR inhibition.
Goldberg AR, Dovas A, Torres D, Pereira B, Viswanathan A, Das Sharma S, Mela A, Merricks EM, Megino-Luque C, McInvale JJ, Olabarria M, Shokooh LA, Zhao HT, Chen C, Kotidis C, Calvaresi P, Banu MA, Razavilar A, Sudhakar TD, Saxena A, Chokran C, Humala N, Mahajan A, Xu W, Metz JB, Bushong EA, Boassa D, Ellisman MH, Hillman EMC, Hargus G, Bravo-Cordero JJ, McKhann GM 2nd, Gill BJA, Rosenfeld SS, Schevon CA, Bruce JN, Sims PA, Peterka DS, Canoll P. Goldberg AR, et al. Among authors: sims pa. Neuron. 2025 Jan 16:S0896-6273(24)00926-7. doi: 10.1016/j.neuron.2024.12.026. Online ahead of print. Neuron. 2025. PMID: 39837324
PRRX1 Has Functional Roles in Pancreatic Acinar to Ductal Metaplasia and Carcinogenesis.
Nishiwaki N, Sugiura K, Suzuki K, Li AL, Tapia Contreras C, Efe G, Shin AE, Sadeghian D, Zhao J, Maitra A, Pitarresi JR, Sims PA, Chandwani R, Rustgi AK. Nishiwaki N, et al. Among authors: sims pa. Cell Mol Gastroenterol Hepatol. 2024 Dec 16:101442. doi: 10.1016/j.jcmgh.2024.101442. Online ahead of print. Cell Mol Gastroenterol Hepatol. 2024. PMID: 39694413 Free article. No abstract available.
Single-cell transcriptomic landscape of the neuroimmune compartment in amyotrophic lateral sclerosis brain and spinal cord.
Tuddenham JF, Fujita M, Khairallah A, Harbison C, Flowers XE, Coronas-Samano G, Maniatis S, Daly A, Schneider JA, Teich AF, Vonsattel JPG, Sims PA, Elyaman W, Bradshaw EM, Phatnani H, Shneider N, Bennett DA, De Jager PL, Przedborski S, Menon V, Olah M. Tuddenham JF, et al. Among authors: sims pa. bioRxiv [Preprint]. 2024 Nov 14:2024.11.12.623183. doi: 10.1101/2024.11.12.623183. bioRxiv. 2024. PMID: 39605399 Free PMC article. Preprint.
Maintenance and functional regulation of immune memory to COVID-19 vaccines in tissues.
Davis-Porada J, George AB, Lam N, Caron DP, Gray JI, Huang J, Hwu J, Wells SB, Matsumoto R, Kubota M, Lee Y, Morrison-Colvin R, Jensen IJ, Ural BB, Shaabani N, Weiskopf D, Grifoni A, Sette A, Szabo PA, Teijaro JR, Sims PA, Farber DL. Davis-Porada J, et al. Among authors: sims pa. Immunity. 2024 Dec 10;57(12):2895-2913.e8. doi: 10.1016/j.immuni.2024.10.003. Epub 2024 Nov 6. Immunity. 2024. PMID: 39510068
HDAC Inhibitors recapitulate Human Disease-Associated Microglia Signatures in vitro.
Haage V, Tuddenham JF, Bautista A, White CC, Garcia F, Patel R, Comandante-Lou N, Marshe V, Soni RK, Sims PA, Menon V, Sproul AA, De Jager PL. Haage V, et al. Among authors: sims pa. bioRxiv [Preprint]. 2024 Oct 12:2024.10.11.617544. doi: 10.1101/2024.10.11.617544. bioRxiv. 2024. PMID: 39416157 Free PMC article. Preprint.
A cross-disease resource of living human microglia identifies disease-enriched subsets and tool compounds recapitulating microglial states.
Tuddenham JF, Taga M, Haage V, Marshe VS, Roostaei T, White C, Lee AJ, Fujita M, Khairallah A, Zhang Y, Green G, Hyman B, Frosch M, Hopp S, Beach TG, Serrano GE, Corboy J, Habib N, Klein HU, Soni RK, Teich AF, Hickman RA, Alcalay RN, Shneider N, Schneider J, Sims PA, Bennett DA, Olah M, Menon V, De Jager PL. Tuddenham JF, et al. Among authors: sims pa. Nat Neurosci. 2024 Dec;27(12):2521-2537. doi: 10.1038/s41593-024-01764-7. Epub 2024 Oct 15. Nat Neurosci. 2024. PMID: 39406950
MAPK/ERK signaling in gliomas modulates interferon responses, T cell recruitment, microglia phenotype, and immune checkpoint blockade efficacy.
Kim KS, Zhang J, Arrieta VA, Dmello C, Grabis E, Habashy K, Duffy J, Zhao J, Gould A, Chen L, Hu J, Balyasnikova I, Chand D, Levey D, Canoll P, Zhao W, Sims PA, Rabadan R, Pandey S, Zhang B, Lee-Chang C, Heiland DH, Sonabend AM. Kim KS, et al. Among authors: sims pa. bioRxiv [Preprint]. 2024 Sep 18:2024.09.11.612571. doi: 10.1101/2024.09.11.612571. bioRxiv. 2024. PMID: 39345374 Free PMC article. Preprint.
129 results