Mertes MP - Search Results

1

Palladium (II)-catalyzed olefin-coupling reactions of kainic acid: effects of substitution on the isopropenyl group on receptor binding.

Conway GA, Park JS, Maggiora L, Mertes MP, Galton N, Michaelis EK. Conway GA, et al. Among authors: mertes mp. J Med Chem. 1984 Jan;27(1):52-6. doi: 10.1021/jm00367a010. J Med Chem. 1984. PMID: 6317861

2

Enzyme affinity of the 5,6-dihydro derivatives of the substrate and product of thymidylate synthetase catalysis.

Park JS, Chang CT, Mertes MP. Park JS, et al. Among authors: mertes mp. J Med Chem. 1979 Mar;22(3):319-21. doi: 10.1021/jm00189a021. J Med Chem. 1979. PMID: 106122

3

Thiol addition to quinones: model reactions for the inactivation of thymidylate synthase by 5-p-benzoquinonyl-2'-deoxyuridine 5'-phosphate.

Vadnere MK, Maggiora L, Mertes MP. Vadnere MK, et al. Among authors: mertes mp. J Med Chem. 1986 Sep;29(9):1714-20. doi: 10.1021/jm00159a025. J Med Chem. 1986. PMID: 3746818

4

5-p-benzoquinonyl-2'-deoxyuridine 5'-phosphate: a possible mechanism-based inhibitor of thymidylate synthetase.

Maggiora L, Chang CT, Hasson ME, Bigge CF, Mertes MP. Maggiora L, et al. Among authors: mertes mp. J Med Chem. 1983 Jul;26(7):1028-36. doi: 10.1021/jm00361a016. J Med Chem. 1983. PMID: 6408258

5

5-[(4-Methyl-1,2,3,4-tetrahydroquinoxalyl)methyl]-2'-deoxyuridine 5'-phosphate: an analogue of a proposed intermediate in thymidylate synthetase catalysis.

Park JS, Chang CT, Mertes MP. Park JS, et al. Among authors: mertes mp. J Med Chem. 1979 Sep;22(9):1134-7. doi: 10.1021/jm00195a027. J Med Chem. 1979. PMID: 114659

6

Polynucleotide analogues. Copolymers of vinyl bases with acrylic acid, methylacrylic acid, acrylamide, and 1-vinylpyrrolidone.

Maggiora L, Boguslawski S, Mertes MP. Maggiora L, et al. Among authors: mertes mp. J Med Chem. 1977 Oct;20(10):1283-7. doi: 10.1021/jm00220a011. J Med Chem. 1977. PMID: 333112

7

Oxime and dithiolane derivatives of 5-formyl-2'-deoxyuridine and their 5'-phosphates: antiviral effects and thymidylate synthetase inhibition.

Park JS, Chang CT, Schmidt CL, Golander Y, De Clercq E, Descamps J, Mertes MP. Park JS, et al. Among authors: mertes mp. J Med Chem. 1980 Jun;23(6):661-5. doi: 10.1021/jm00180a016. J Med Chem. 1980. PMID: 6248643

8

Pharmacological specificity of synaptosomal and synaptic membrane gamma-aminobutyric acid (GABA) transport processes.

Early SL, Michaelis EK, Mertes MP. Early SL, et al. Among authors: mertes mp. Biochem Pharmacol. 1981 May 15;30(10):1105-13. doi: 10.1016/0006-2952(81)90449-4. Biochem Pharmacol. 1981. PMID: 7259793 No abstract available.

9

5-Quinone derivatives of 2'-deoxyuridine 5'-phosphate: inhibition and inactivation of thymidylate synthase, antitumor cell, and antiviral studies.

Al-Razzak LA, Schwepler D, Decedue CJ, Balzarini J, De Clercq E, Mertes MP. Al-Razzak LA, et al. Among authors: mertes mp. J Med Chem. 1987 Feb;30(2):409-19. doi: 10.1021/jm00385a026. J Med Chem. 1987. PMID: 3027341

10

Linear free energy relationship studies of enzyme active site binding: thymidylate synthase.

Chang G, Schwepler D, Decedue CJ, Balzarini J, De Clercq E, Mertes MP. Chang G, et al. Among authors: mertes mp. J Med Chem. 1988 Jun;31(6):1141-7. doi: 10.1021/jm00401a013. J Med Chem. 1988. PMID: 3373483

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