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Biological effects of modified colchicines. Improved preparation of 2-demethylcolchicine, 3-demethylcolchicine, and (+)-colchicine and reassignment of the position of the double bond in dehydro-7-deacetamidocolchicines.
Rösner M, Capraro HG, Jacobson AE, Atwell L, Brossi A, Iorio MA, Williams TH, Sik RH, Chignell CF. Rösner M, et al. Among authors: chignell cf. J Med Chem. 1981 Mar;24(3):257-61. doi: 10.1021/jm00135a005. J Med Chem. 1981. PMID: 7265112
Synthesis and biological effects of novel thiocolchicines. 3. Evaluation of N-acyldeacetylthiocolchicines, N-(alkoxycarbonyl) deacetylthiocolchicines, and O-ethyldemethylthiocolchicines. New synthesis of thiodemecolcine and antileukemic effects of 2-demethyl- and 3-demethylthiocolchicine.
Kerekes P, Sharma PN, Brossi A, Chignell CF, Quinn FR. Kerekes P, et al. Among authors: chignell cf. J Med Chem. 1985 Sep;28(9):1204-8. doi: 10.1021/jm00147a014. J Med Chem. 1985. PMID: 4032423
217 results