Tozer MJ - Search Results

1

Improving the affinity and selectivity of a nonpeptide series of cholecystokinin-B/gastrin receptor antagonists based on the dibenzobicyclo[2.2.2]octane skeleton.

Kalindjian SB, Buck IM, Cushnir JR, Dunstone DJ, Hudson ML, Low CM, McDonald IM, Pether MJ, Steel KI, Tozer MJ. Kalindjian SB, et al. Among authors: tozer mj. J Med Chem. 1995 Oct 13;38(21):4294-302. doi: 10.1021/jm00021a019. J Med Chem. 1995. PMID: 7473557

2

omega-(Imidazol-4-yl)alkane-1-sulfonamides: a new series of potent histamine H(3) receptor antagonists.

Tozer MJ, Buck IM, Cooke T, Kalindjian SB, Pether MJ, Steel KI. Tozer MJ, et al. Bioorg Med Chem. 2002 Feb;10(2):425-32. doi: 10.1016/s0968-0896(01)00295-4. Bioorg Med Chem. 2002. PMID: 11741790

3

CCK(2) receptor antagonists containing the conformationally constrained phenylalanine derivatives, including the new amino acid Xic.

Gibson SE, Guillo N, Jones JO, Buck IM, Kalindjian SB, Roberts S, Tozer MJ. Gibson SE, et al. Among authors: tozer mj. Eur J Med Chem. 2002 May;37(5):379-89. doi: 10.1016/s0223-5234(02)01351-x. Eur J Med Chem. 2002. PMID: 12008052

4

Optimization of the in vitro and in vivo properties of a novel series of 2,4,5-trisubstituted imidazoles as potent cholecystokinin-2 (CCK2) antagonists.

Buck IM, Black JW, Cooke T, Dunstone DJ, Gaffen JD, Griffin EP, Harper EA, Hull RA, Kalindjian SB, Lilley EJ, Linney ID, Low CM, McDonald IM, Pether MJ, Roberts SP, Shankley NP, Shaxted ME, Steel KI, Sykes DA, Tozer MJ, Watt GF, Walker MK, Wright L, Wright PT. Buck IM, et al. Among authors: tozer mj. J Med Chem. 2005 Nov 3;48(22):6803-12. doi: 10.1021/jm0490686. J Med Chem. 2005. PMID: 16250639

5

Non-peptide cholecystokinin-B/gastrin receptor antagonists based on bicyclic, heteroaromatic skeletons.

Kalindjian SB, Buck IM, Davies JM, Dunstone DJ, Hudson ML, Low CM, McDonald IM, Pether MJ, Steel KI, Tozer MJ, Vinter JG. Kalindjian SB, et al. Among authors: tozer mj. J Med Chem. 1996 Apr 26;39(9):1806-15. doi: 10.1021/jm9508907. J Med Chem. 1996. PMID: 8627604

6

From histamine to imidazolylalkyl-sulfonamides: the design of a novel series of histamine H3-receptor antagonists.

Tozer MJ, Harper EA, Kalindjian SB, Pether MJ, Shankley NP, Watt GF. Tozer MJ, et al. Bioorg Med Chem Lett. 1999 Jul 5;9(13):1825-30. doi: 10.1016/s0960-894x(99)00272-3. Bioorg Med Chem Lett. 1999. PMID: 10406649

7

4-Chlorobenzyl sulfonamide and sulfamide derivatives of histamine homologues: the design of potent histamine H3 receptor antagonists.

Tozer MJ, Buck IM, Cooke T, Kalindjian SB, McDonald IM, Pether MJ, Steel KI. Tozer MJ, et al. Bioorg Med Chem Lett. 1999 Nov 1;9(21):3103-8. doi: 10.1016/s0960-894x(99)00535-1. Bioorg Med Chem Lett. 1999. PMID: 10560733

8

2,7-Dioxo-2,3,4,5,6,7-hexahydro-1H-benzo[h][1,4]diazonine as a new template for the design of CCK(2) receptor antagonists.

McDonald IM, Dunstone DJ, Kalindjian SB, Linney ID, Low CM, Pether MJ, Steel KI, Tozer MJ, Vinter JG. McDonald IM, et al. Among authors: tozer mj. J Med Chem. 2000 Sep 21;43(19):3518-29. doi: 10.1021/jm000960w. J Med Chem. 2000. PMID: 11000006

9

Nonpeptide cholecystokinin-2 receptor agonists.

Kalindjian SB, Dunstone DJ, Low CM, Pether MJ, Roberts SP, Tozer MJ, Watt GF, Shankley NP. Kalindjian SB, et al. Among authors: tozer mj. J Med Chem. 2001 Apr 12;44(8):1125-33. doi: 10.1021/jm0010668. J Med Chem. 2001. PMID: 11312913

10

Synthesis and structural analysis of dehydrophenylalanine cyclophanes.

Gibson SE, Jones JO, Kalindjian SB, Knight JD, Steed JW, Tozer MJ. Gibson SE, et al. Among authors: tozer mj. Chem Commun (Camb). 2002 Sep 7;(17):1938-9. doi: 10.1039/b205752m. Chem Commun (Camb). 2002. PMID: 12271683

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