Wittinghofer A - Search Results

1

Direct stimulation of Vav guanine nucleotide exchange activity for Ras by phorbol esters and diglycerides.

Gulbins E, Coggeshall KM, Baier G, Telford D, Langlet C, Baier-Bitterlich G, Bonnefoy-Berard N, Burn P, Wittinghofer A, Altman A. Gulbins E, et al. Among authors: wittinghofer a. Mol Cell Biol. 1994 Jul;14(7):4749-58. doi: 10.1128/mcb.14.7.4749-4758.1994. Mol Cell Biol. 1994. PMID: 7516472 Free PMC article.

2

Activation of Ras in vitro and in intact fibroblasts by the Vav guanine nucleotide exchange protein.

Gulbins E, Coggeshall KM, Langlet C, Baier G, Bonnefoy-Berard N, Burn P, Wittinghofer A, Katzav S, Altman A. Gulbins E, et al. Among authors: wittinghofer a. Mol Cell Biol. 1994 Feb;14(2):906-13. doi: 10.1128/mcb.14.2.906-913.1994. Mol Cell Biol. 1994. PMID: 8289830 Free PMC article.

3

Model of the ran-RCC1 interaction using biochemical and docking experiments.

Azuma Y, Renault L, García-Ranea JA, Valencia A, Nishimoto T, Wittinghofer A. Azuma Y, et al. Among authors: wittinghofer a. J Mol Biol. 1999 Jun 18;289(4):1119-30. doi: 10.1006/jmbi.1999.2820. J Mol Biol. 1999. PMID: 10369786

4

The Ras mutant D119N is both dominant negative and activated.

Cool RH, Schmidt G, Lenzen CU, Prinz H, Vogt D, Wittinghofer A. Cool RH, et al. Among authors: wittinghofer a. Mol Cell Biol. 1999 Sep;19(9):6297-305. doi: 10.1128/MCB.19.9.6297. Mol Cell Biol. 1999. PMID: 10454576 Free PMC article.

5

The RafC1 cysteine-rich domain contains multiple distinct regulatory epitopes which control Ras-dependent Raf activation.

Daub M, Jöckel J, Quack T, Weber CK, Schmitz F, Rapp UR, Wittinghofer A, Block C. Daub M, et al. Among authors: wittinghofer a. Mol Cell Biol. 1998 Nov;18(11):6698-710. doi: 10.1128/MCB.18.11.6698. Mol Cell Biol. 1998. PMID: 9774683 Free PMC article.

6

The role of the conserved switch II glutamate in guanine nucleotide exchange factor-mediated nucleotide exchange of GTP-binding proteins.

Gasper R, Thomas C, Ahmadian MR, Wittinghofer A. Gasper R, et al. Among authors: wittinghofer a. J Mol Biol. 2008 May 23;379(1):51-63. doi: 10.1016/j.jmb.2008.03.011. Epub 2008 Mar 14. J Mol Biol. 2008. PMID: 18440551

7

Fluorescently labelled guanine nucleotide binding proteins to analyse elementary steps of GAP-catalysed reactions.

Kraemer A, Brinkmann T, Plettner I, Goody R, Wittinghofer A. Kraemer A, et al. Among authors: wittinghofer a. J Mol Biol. 2002 Dec 6;324(4):763-74. doi: 10.1016/s0022-2836(02)01136-1. J Mol Biol. 2002. PMID: 12460576

8

Dynamic interaction of cAMP with the Rap guanine-nucleotide exchange factor Epac1.

Kraemer A, Rehmann HR, Cool RH, Theiss C, de Rooij J, Bos JL, Wittinghofer A. Kraemer A, et al. Among authors: wittinghofer a. J Mol Biol. 2001 Mar 9;306(5):1167-77. doi: 10.1006/jmbi.2001.4444. J Mol Biol. 2001. PMID: 11237625

9

Regulation of Cdc2/cyclin B activation by Ran, a Ras-related GTPase.

Clarke PR, Klebe C, Wittinghofer A, Karsenti E. Clarke PR, et al. Among authors: wittinghofer a. J Cell Sci. 1995 Mar;108 ( Pt 3):1217-25. doi: 10.1242/jcs.108.3.1217. J Cell Sci. 1995. PMID: 7622606

10

A Rap/phosphatidylinositol 3-kinase pathway controls pseudopod formation [corrected].

Kortholt A, Bolourani P, Rehmann H, Keizer-Gunnink I, Weeks G, Wittinghofer A, Van Haastert PJ. Kortholt A, et al. Among authors: wittinghofer a. Mol Biol Cell. 2010 Mar 15;21(6):936-45. doi: 10.1091/mbc.e09-03-0177. Epub 2010 Jan 20. Mol Biol Cell. 2010. PMID: 20089846 Free PMC article.

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