Rosenfeld MA - Search Results

1

Gene transfer to freshly isolated human respiratory epithelial cells in vitro using a replication-deficient adenovirus containing the human cystic fibrosis transmembrane conductance regulator cDNA.

Rosenfeld MA, Chu CS, Seth P, Danel C, Banks T, Yoneyama K, Yoshimura K, Crystal RG. Rosenfeld MA, et al. Hum Gene Ther. 1994 Mar;5(3):331-42. doi: 10.1089/hum.1994.5.3-331. Hum Gene Ther. 1994. PMID: 7517189

2

Mechanism of enhancement of DNA expression consequent to cointernalization of a replication-deficient adenovirus and unmodified plasmid DNA.

Seth P, Rosenfeld M, Higginbotham J, Crystal RG. Seth P, et al. J Virol. 1994 Feb;68(2):933-40. doi: 10.1128/JVI.68.2.933-940.1994. J Virol. 1994. PMID: 7507187 Free PMC article.

3

A phase 1 study, in cystic fibrosis patients, of the safety, toxicity, and biological efficacy of a single administration of a replication deficient, recombinant adenovirus carrying the cDNA of the normal cystic fibrosis transmembrane conductance regulator gene in the lung.

Crystal RG, Jaffe A, Brody S, Mastrangeli A, McElvaney NG, Rosenfeld M, Chu CS, Danel C, Hay J, Eissa T. Crystal RG, et al. Hum Gene Ther. 1995 May;6(5):643-66. doi: 10.1089/hum.1995.6.5-643. Hum Gene Ther. 1995. PMID: 7578401 No abstract available.

4

Polarity of secretion of alpha 1-antitrypsin by human respiratory epithelial cells after adenoviral transfer of a human alpha 1-antitrypsin cDNA.

Siegfried W, Rosenfeld M, Stier L, Stratford-Perricaudet L, Perricaudet M, Pavirani A, Lecocq JP, Crystal RG. Siegfried W, et al. Am J Respir Cell Mol Biol. 1995 Apr;12(4):379-84. doi: 10.1165/ajrcmb.12.4.7695917. Am J Respir Cell Mol Biol. 1995. PMID: 7695917

5

In vivo transfer of the human cystic fibrosis transmembrane conductance regulator gene to the airway epithelium.

Rosenfeld MA, Yoshimura K, Trapnell BC, Yoneyama K, Rosenthal ER, Dalemans W, Fukayama M, Bargon J, Stier LE, Stratford-Perricaudet L, et al. Rosenfeld MA, et al. Cell. 1992 Jan 10;68(1):143-55. doi: 10.1016/0092-8674(92)90213-v. Cell. 1992. PMID: 1370653

6

Expression of the human cystic fibrosis transmembrane conductance regulator gene in the mouse lung after in vivo intratracheal plasmid-mediated gene transfer.

Yoshimura K, Rosenfeld MA, Nakamura H, Scherer EM, Pavirani A, Lecocq JP, Crystal RG. Yoshimura K, et al. Among authors: rosenfeld ma. Nucleic Acids Res. 1992 Jun 25;20(12):3233-40. doi: 10.1093/nar/20.12.3233. Nucleic Acids Res. 1992. PMID: 1377820 Free PMC article.

7

Adenovirus-mediated transfer of a recombinant alpha 1-antitrypsin gene to the lung epithelium in vivo.

Rosenfeld MA, Siegfried W, Yoshimura K, Yoneyama K, Fukayama M, Stier LE, Pääkkö PK, Gilardi P, Stratford-Perricaudet LD, Perricaudet M, et al. Rosenfeld MA, et al. Science. 1991 Apr 19;252(5004):431-4. doi: 10.1126/science.2017680. Science. 1991. PMID: 2017680

8

Acute responses of non-human primates to airway delivery of an adenovirus vector containing the human cystic fibrosis transmembrane conductance regulator cDNA.

Brody SL, Metzger M, Danel C, Rosenfeld MA, Crystal RG. Brody SL, et al. Among authors: rosenfeld ma. Hum Gene Ther. 1994 Jul;5(7):821-36. doi: 10.1089/hum.1994.5.7-821. Hum Gene Ther. 1994. PMID: 7526901

9

Administration of an adenovirus containing the human CFTR cDNA to the respiratory tract of individuals with cystic fibrosis.

Crystal RG, McElvaney NG, Rosenfeld MA, Chu CS, Mastrangeli A, Hay JG, Brody SL, Jaffe HA, Eissa NT, Danel C. Crystal RG, et al. Among authors: rosenfeld ma. Nat Genet. 1994 Sep;8(1):42-51. doi: 10.1038/ng0994-42. Nat Genet. 1994. PMID: 7527271 Clinical Trial.

10

Increasing expression of the normal human CFTR cDNA in cystic fibrosis epithelial cells results in a progressive increase in the level of CFTR protein expression, but a limit on the level of cAMP-stimulated chloride secretion.

Rosenfeld MA, Rosenfeld SJ, Danel C, Banks TC, Crystal RG. Rosenfeld MA, et al. Among authors: rosenfeld sj. Hum Gene Ther. 1994 Sep;5(9):1121-9. doi: 10.1089/hum.1994.5.9-1121. Hum Gene Ther. 1994. PMID: 7530494

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