Jäger J - Search Results

1

Two DNA polymerases: HIV reverse transcriptase and the Klenow fragment of Escherichia coli DNA polymerase I.

Steitz TA, Smerdon S, Jäger J, Wang J, Kohlstaedt LA, Friedman JM, Beese LS, Rice PA. Steitz TA, et al. Among authors: jager j. Cold Spring Harb Symp Quant Biol. 1993;58:495-504. doi: 10.1101/sqb.1993.058.01.056. Cold Spring Harb Symp Quant Biol. 1993. PMID: 7525146 No abstract available.

2

Structure of the binding site for nonnucleoside inhibitors of the reverse transcriptase of human immunodeficiency virus type 1.

Smerdon SJ, Jäger J, Wang J, Kohlstaedt LA, Chirino AJ, Friedman JM, Rice PA, Steitz TA. Smerdon SJ, et al. Among authors: jager j. Proc Natl Acad Sci U S A. 1994 Apr 26;91(9):3911-5. doi: 10.1073/pnas.91.9.3911. Proc Natl Acad Sci U S A. 1994. PMID: 7513427 Free PMC article.

3

Structural basis of asymmetry in the human immunodeficiency virus type 1 reverse transcriptase heterodimer.

Wang J, Smerdon SJ, Jäger J, Kohlstaedt LA, Rice PA, Friedman JM, Steitz TA. Wang J, et al. Among authors: jager j. Proc Natl Acad Sci U S A. 1994 Jul 19;91(15):7242-6. doi: 10.1073/pnas.91.15.7242. Proc Natl Acad Sci U S A. 1994. PMID: 7518928 Free PMC article.

4

Comparison of three different crystal forms shows HIV-1 reverse transcriptase displays an internal swivel motion.

Jäger J, Smerdon SJ, Wang J, Boisvert DC, Steitz TA. Jäger J, et al. Structure. 1994 Sep 15;2(9):869-76. doi: 10.1016/s0969-2126(94)00087-5. Structure. 1994. PMID: 7529124

5

A unified polymerase mechanism for nonhomologous DNA and RNA polymerases.

Steitz TA, Smerdon SJ, Jäger J, Joyce CM. Steitz TA, et al. Among authors: jager j. Science. 1994 Dec 23;266(5193):2022-5. doi: 10.1126/science.7528445. Science. 1994. PMID: 7528445 No abstract available.

6

Threonine 79 is a hinge residue that governs the fidelity of DNA polymerase beta by helping to position the DNA within the active site.

Maitra M, Gudzelak A Jr, Li SX, Matsumoto Y, Eckert KA, Jager J, Sweasy JB. Maitra M, et al. Among authors: jager j. J Biol Chem. 2002 Sep 20;277(38):35550-60. doi: 10.1074/jbc.M204953200. Epub 2002 Jul 16. J Biol Chem. 2002. PMID: 12121998 Free article.

7

A DNA polymerase beta mutator mutant with reduced nucleotide discrimination and increased protein stability.

Shah AM, Conn DA, Li SX, Capaldi A, Jäger J, Sweasy JB. Shah AM, et al. Among authors: jager j. Biochemistry. 2001 Sep 25;40(38):11372-81. doi: 10.1021/bi010755y. Biochemistry. 2001. PMID: 11560485

8

Getting a grip: polymerases and their substrate complexes.

Jäger J, Pata JD. Jäger J, et al. Curr Opin Struct Biol. 1999 Feb;9(1):21-8. doi: 10.1016/s0959-440x(99)80004-9. Curr Opin Struct Biol. 1999. PMID: 10047577 Review.

9

Substrate complexes of hepatitis C virus RNA polymerase (HC-J4): structural evidence for nucleotide import and de-novo initiation.

O'Farrell D, Trowbridge R, Rowlands D, Jäger J. O'Farrell D, et al. Among authors: jager j. J Mol Biol. 2003 Feb 28;326(4):1025-35. doi: 10.1016/s0022-2836(02)01439-0. J Mol Biol. 2003. PMID: 12589751

10

Structural plasticity and noncovalent substrate binding in the GroEL apical domain. A study using electrospay ionization mass spectrometry and fluorescence binding studies.

Ashcroft AE, Brinker A, Coyle JE, Weber F, Kaiser M, Moroder L, Parsons MR, Jager J, Hartl UF, Hayer-Hartl M, Radford SE. Ashcroft AE, et al. Among authors: jager j. J Biol Chem. 2002 Sep 6;277(36):33115-26. doi: 10.1074/jbc.M203398200. Epub 2002 Jun 13. J Biol Chem. 2002. PMID: 12065585 Free article.

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