Born SL - Search Results

1

Characterization of the progesterone 21-hydroxylase activity of canine cytochrome P450 PBD-2/P450 2B11 through reconstitution, heterologous expression, and site-directed mutagenesis.

Born SL, John GH, Harlow GR, Halpert JR. Born SL, et al. Drug Metab Dispos. 1995 Jul;23(7):702-7. Drug Metab Dispos. 1995. PMID: 7587957

2

Escherichia coli expression and substrate specificities of canine cytochrome P450 3A12 and rabbit cytochrome P450 3A6.

Born SL, Fraser DJ, Harlow GR, Halpert JR. Born SL, et al. J Pharmacol Exp Ther. 1996 Aug;278(2):957-63. J Pharmacol Exp Ther. 1996. PMID: 8768753

3

Suppression of rat hepatic microsomal cytochromes P450 by cyclophosphamide is correlated with plasma thyroid hormone levels and displays differential strain sensitivity.

Kraner JC, Morgan ET, Poet TS, Born SL, Burnett VL, Halpert JR. Kraner JC, et al. Among authors: born sl. J Pharmacol Exp Ther. 1996 Jan;276(1):258-64. J Pharmacol Exp Ther. 1996. PMID: 8558440

4

Identification of the cytochromes P450 that catalyze coumarin 3,4-epoxidation and 3-hydroxylation.

Born SL, Caudill D, Fliter KL, Purdon MP. Born SL, et al. Drug Metab Dispos. 2002 May;30(5):483-7. doi: 10.1124/dmd.30.5.483. Drug Metab Dispos. 2002. PMID: 11950775

5

o-hydroxyphenylacetaldehyde is a hepatotoxic metabolite of coumarin.

Born SL, Hu JK, Lehman-McKeeman LD. Born SL, et al. Drug Metab Dispos. 2000 Feb;28(2):218-23. Drug Metab Dispos. 2000. PMID: 10640521

6

Synthesis and reactivity of coumarin 3,4-epoxide.

Born SL, Rodriguez PA, Eddy CL, Lehman-McKeeman LD. Born SL, et al. Drug Metab Dispos. 1997 Nov;25(11):1318-24. Drug Metab Dispos. 1997. PMID: 9351910

7

Development of tolerance to Clara cell necrosis with repeat administration of coumarin.

Born SL, Fix AS, Caudill D, Lehman-McKeeman LD. Born SL, et al. Toxicol Sci. 1999 Oct;51(2):300-9. doi: 10.1093/toxsci/51.2.300. Toxicol Sci. 1999. PMID: 10543032

8

In vitro kinetics of coumarin 3,4-epoxidation: application to species differences in toxicity and carcinogenicity.

Born SL, Caudill D, Smith BJ, Lehman-McKeeman LD. Born SL, et al. Toxicol Sci. 2000 Nov;58(1):23-31. doi: 10.1093/toxsci/58.1.23. Toxicol Sci. 2000. PMID: 11053537

9

Selective Clara cell injury in mouse lung following acute administration of coumarin.

Born SL, Fix AS, Caudill D, Lehman-McKeeman LD. Born SL, et al. Toxicol Appl Pharmacol. 1998 Jul;151(1):45-56. doi: 10.1006/taap.1998.8442. Toxicol Appl Pharmacol. 1998. PMID: 9705886

10

Roles for epoxidation and detoxification of coumarin in determining species differences in clara cell toxicity.

Vassallo JD, Hicks SM, Born SL, Daston GP. Vassallo JD, et al. Among authors: born sl. Toxicol Sci. 2004 Nov;82(1):26-33. doi: 10.1093/toxsci/kfh237. Epub 2004 Jul 28. Toxicol Sci. 2004. PMID: 15282406

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