Molecular genetic analysis reveals chromosomal deletion, gene amplification, and autocrine growth factor production in the pathogenesis of human lung cancer.
Minna JD, Battey JF, Brooks BJ, Cuttitta F, Gazdar AF, Johnson BE, Ihde DC, Lebacq-Verheyden AM, Mulshine J, Nau MM, et al.
Minna JD, et al. Among authors: johnson be.
Cold Spring Harb Symp Quant Biol. 1986;51 Pt 2:843-53. doi: 10.1101/sqb.1986.051.01.098.
Cold Spring Harb Symp Quant Biol. 1986.
PMID: 3472765
These studies of lung cancer suggest that a number of molecular mechanisms may be important in the pathogenesis of lung cancer, especially SCLC. An inherited predisposition to develop SCLC may correlate with a nonfunctional, recessive allele for a gene (McKusick #18228, Mc …
These studies of lung cancer suggest that a number of molecular mechanisms may be important in the pathogenesis of lung cancer, espec …