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Ribozyme-mediated RNA degradation in nuclei suspension.
Heidenreich O, Kang SH, Brown DA, Xu X, Swiderski P, Rossi JJ, Eckstein F, Nerenberg M. Heidenreich O, et al. Among authors: eckstein f. Nucleic Acids Res. 1995 Jun 25;23(12):2223-8. doi: 10.1093/nar/23.12.2223. Nucleic Acids Res. 1995. PMID: 7610051 Free PMC article.
Chemically modified RNA: approaches and applications.
Heidenreich O, Pieken W, Eckstein F. Heidenreich O, et al. Among authors: eckstein f. FASEB J. 1993 Jan;7(1):90-6. doi: 10.1096/fasebj.7.1.7678566. FASEB J. 1993. PMID: 7678566 Review.
High activity and stability of hammerhead ribozymes containing 2'-modified pyrimidine nucleosides and phosphorothioates.
Heidenreich O, Benseler F, Fahrenholz A, Eckstein F. Heidenreich O, et al. Among authors: eckstein f. J Biol Chem. 1994 Jan 21;269(3):2131-8. J Biol Chem. 1994. PMID: 8294467 Free article.
Previous studies had shown that substitution of all pyrimidine nucleosides by their 2'-fluoro analogs led to an 8-fold decrease in catalytic efficiency in the cleavage reaction compared to the unmodified ribozyme (Heidenreich, O., and Eckstein, F. (1992) J. Biol. Ch …
Previous studies had shown that substitution of all pyrimidine nucleosides by their 2'-fluoro analogs led to an 8-fold decrease in catalytic …
Recent developments in the hammerhead ribozyme field.
Vaish NK, Kore AR, Eckstein F. Vaish NK, et al. Among authors: eckstein f. Nucleic Acids Res. 1998 Dec 1;26(23):5237-42. doi: 10.1093/nar/26.23.5237. Nucleic Acids Res. 1998. PMID: 9826743 Free PMC article. Review.
978 results