Rasmusson GH - Search Results

1

4-Aza-3-oxo-5 alpha-androst-1-ene-17 beta-N-aryl-carboxamides as dual inhibitors of human type 1 and type 2 steroid 5 alpha-reductases. Dramatic effect of N-aryl substituents on type 1 and type 2 5 alpha-reductase inhibitory potency.

Bakshi RK, Rasmusson GH, Patel GF, Mosley RT, Chang B, Ellsworth K, Harris GS, Tolman RL. Bakshi RK, et al. Among authors: rasmusson gh. J Med Chem. 1995 Aug 18;38(17):3189-92. doi: 10.1021/jm00017a001. J Med Chem. 1995. PMID: 7650670 No abstract available.

2

4,7 beta-Dimethyl-4-azacholestan-3-one (MK-386) and related 4-azasteroids as selective inhibitors of human type 1 5 alpha-reductase.

Bakshi RK, Patel GF, Rasmusson GH, Baginsky WF, Cimis G, Ellsworth K, Chang B, Bull H, Tolman RL, Harris GS. Bakshi RK, et al. Among authors: rasmusson gh. J Med Chem. 1994 Nov 11;37(23):3871-4. doi: 10.1021/jm00049a003. J Med Chem. 1994. PMID: 7966146 No abstract available.

3

Azasteroids: structure-activity relationships for inhibition of 5 alpha-reductase and of androgen receptor binding.

Rasmusson GH, Reynolds GF, Steinberg NG, Walton E, Patel GF, Liang T, Cascieri MA, Cheung AH, Brooks JR, Berman C. Rasmusson GH, et al. J Med Chem. 1986 Nov;29(11):2298-315. doi: 10.1021/jm00161a028. J Med Chem. 1986. PMID: 3783591

4

Identification and selective inhibition of an isozyme of steroid 5 alpha-reductase in human scalp.

Harris G, Azzolina B, Baginsky W, Cimis G, Rasmusson GH, Tolman RL, Raetz CR, Ellsworth K. Harris G, et al. Among authors: rasmusson gh. Proc Natl Acad Sci U S A. 1992 Nov 15;89(22):10787-91. doi: 10.1073/pnas.89.22.10787. Proc Natl Acad Sci U S A. 1992. PMID: 1438277 Free PMC article.

5

Comparison of the effects of new specific azasteroid inhibitors of steroid 5 alpha-reductase on canine hyperplastic prostate: suppression of prostatic DHT correlated with prostate regression.

Cohen SM, Werrmann JG, Rasmusson GH, Tanaka WK, Malatesta PF, Prahalada S, Jacobs JG, Harris G, Nett TM. Cohen SM, et al. Among authors: rasmusson gh. Prostate. 1995 Feb;26(2):55-71. doi: 10.1002/pros.2990260202. Prostate. 1995. PMID: 7531846

6

Azasteroids as inhibitors of testosterone 5 alpha-reductase in mammalian skin.

Mellin TN, Busch RD, Rasmusson GH. Mellin TN, et al. Among authors: rasmusson gh. J Steroid Biochem Mol Biol. 1993 Feb;44(2):121-31. doi: 10.1016/0960-0760(93)90019-s. J Steroid Biochem Mol Biol. 1993. PMID: 8439517

7

Azasteroids as inhibitors of rat prostatic 5 alpha-reductase.

Rasmusson GH, Reynolds GF, Utne T, Jobson RB, Primka RL, Berman C, Brooks JR. Rasmusson GH, et al. J Med Chem. 1984 Dec;27(12):1690-701. doi: 10.1021/jm00378a028. J Med Chem. 1984. PMID: 6502599

8

Effect of castration, DES, flutamide, and the 5 alpha-reductase inhibitor, MK-906, on the growth of the Dunning rat prostatic carcinoma, R-3327.

Brooks JR, Berman C, Nguyen H, Prahalada S, Primka RL, Rasmusson GH, Slater EE. Brooks JR, et al. Among authors: rasmusson gh. Prostate. 1991;18(3):215-27. doi: 10.1002/pros.2990180304. Prostate. 1991. PMID: 1850515

9

Identification of human cytochrome P450 isozymes responsible for the in vitro oxidative metabolism of finasteride.

Huskey SW, Dean DC, Miller RR, Rasmusson GH, Chiu SH. Huskey SW, et al. Among authors: rasmusson gh. Drug Metab Dispos. 1995 Oct;23(10):1126-35. Drug Metab Dispos. 1995. PMID: 8654202

10

4-Azasteroidal 5 alpha-reductase inhibitors without affinity for the androgen receptor.

Liang T, Heiss CE, Cheung AH, Reynolds GF, Rasmusson GH. Liang T, et al. Among authors: rasmusson gh. J Biol Chem. 1984 Jan 25;259(2):734-9. J Biol Chem. 1984. PMID: 6693392 Free article.

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