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Radiometal labeling of recombinant proteins by a genetically engineered minimal chelation site: technetium-99m coordination by single-chain Fv antibody fusion proteins through a C-terminal cysteinyl peptide.
George AJ, Jamar F, Tai MS, Heelan BT, Adams GP, McCartney JE, Houston LL, Weiner LM, Oppermann H, Peters AM. George AJ, et al. Among authors: adams gp. Proc Natl Acad Sci U S A. 1995 Aug 29;92(18):8358-62. doi: 10.1073/pnas.92.18.8358. Proc Natl Acad Sci U S A. 1995. PMID: 7667295 Free PMC article.
Single-chain Fv radioimmunotargeting.
Huston JS, George AJ, Adams GP, Stafford WF, Jamar F, Tai MS, McCartney JE, Oppermann H, Heelan BT, Peters AM, Houston LL, Bookman MA, Wolf EJ, Weiner LM. Huston JS, et al. Among authors: adams gp. Q J Nucl Med. 1996 Sep;40(3):320-33. Q J Nucl Med. 1996. PMID: 8961808 Review.
Engineering disulfide-linked single-chain Fv dimers [(sFv')2] with improved solution and targeting properties: anti-digoxin 26-10 (sFv')2 and anti-c-erbB-2 741F8 (sFv')2 made by protein folding and bonded through C-terminal cysteinyl peptides.
McCartney JE, Tai MS, Hudziak RM, Adams GP, Weiner LM, Jin D, Stafford WF 3rd, Liu S, Bookman MA, Laminet AA, et al. McCartney JE, et al. Among authors: adams gp. Protein Eng. 1995 Mar;8(3):301-14. doi: 10.1093/protein/8.3.301. Protein Eng. 1995. PMID: 7479692
274 results