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An inhibitor of mTOR reduces neoplasia and normalizes p70/S6 kinase activity in Pten+/- mice.
Podsypanina K, Lee RT, Politis C, Hennessy I, Crane A, Puc J, Neshat M, Wang H, Yang L, Gibbons J, Frost P, Dreisbach V, Blenis J, Gaciong Z, Fisher P, Sawyers C, Hedrick-Ellenson L, Parsons R. Podsypanina K, et al. Among authors: fisher p. Proc Natl Acad Sci U S A. 2001 Aug 28;98(18):10320-5. doi: 10.1073/pnas.171060098. Epub 2001 Aug 14. Proc Natl Acad Sci U S A. 2001. PMID: 11504907 Free PMC article.
Mutation of Pten/Mmac1 in mice causes neoplasia in multiple organ systems.
Podsypanina K, Ellenson LH, Nemes A, Gu J, Tamura M, Yamada KM, Cordon-Cardo C, Catoretti G, Fisher PE, Parsons R. Podsypanina K, et al. Among authors: fisher pe. Proc Natl Acad Sci U S A. 1999 Feb 16;96(4):1563-8. doi: 10.1073/pnas.96.4.1563. Proc Natl Acad Sci U S A. 1999. PMID: 9990064 Free PMC article.
T helper 2 cell-directed immunotherapy eliminates precancerous skin lesions.
Oka T, Smith SS, Son HG, Lee T, Oliver-Garcia VS, Mortaja M, Trerice KE, Isakoff LS, Conrad DN, Azin M, Raval NS, Tabacchi M, Emdad L, Das SK, Fisher PB, Cornelius LA, Demehri S. Oka T, et al. Among authors: fisher pb. J Clin Invest. 2025 Jan 2;135(1):e183274. doi: 10.1172/JCI183274. J Clin Invest. 2025. PMID: 39744942 Free PMC article.
2,443 results